Catalog: KE1172
Size
Price
Status
Qty.
5*96well
$1,850.00
2 weeks
0
2*96well
$740.00
2 weeks
0
96well
$370.00
2 weeks
0
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Main Information
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Unmodified
Detailed Information
Specificity
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Storage
2-8°C/6 months,Ship by ice bag
Modification
Unmodified
Sample Type
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Detection Method
Colorimetric
Detection Range
0.1-10ng/mL
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RS0002
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β-actin (PTR2364) Mouse mAb
YM3028
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Antigen&Target Information
Specificity:
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
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Gene Name:
MMP3
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Protein Name:
Stromelysin-1
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Other Name:
MMP3 ;
STMY1 ;
Stromelysin-1 ;
SL-1 ;
Matrix metalloproteinase-3 ;
MMP-3 ;
Transin-1
STMY1 ;
Stromelysin-1 ;
SL-1 ;
Matrix metalloproteinase-3 ;
MMP-3 ;
Transin-1
show all
Background:
catalytic activity:Preferential cleavage where P1' , P2' and P3' are hydrophobic residues. ,cofactor:Binds 2 zinc ions per subunit. ,cofactor:Binds 4 calcium ions per subunit. ,domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion , thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme. ,function:Can degrade fibronectin , laminin , gelatins of type I , III , IV , and V; collagens III , IV , X , and IX , and cartilage proteoglycans. Activates procollagenase. ,similarity:Belongs to the peptidase M10A family. ,similarity:Contains 4 hemopexin-like domains. ,
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Function:
response to acid , proteolysis , response to endogenous stimulus , response to organic substance , response to organic nitrogen , response to amine stimulus , collagen catabolic process , collagen metabolic process , response to cytokine stimulus , response to amino acid stimulus , multicellular organismal metabolic process , multicellular organismal catabolic process , multicellular organismal macromolecule metabolic process ,
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Cellular Localization:
Secreted , extracellular space , extracellular matrix .
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Signaling Pathway
Organismal Systems >> Immune system >> IL-17 signaling pathway
Human Diseases >> Cancer: overview >> Transcriptional misregulation in cancer
Human Diseases >> Cancer: specific types >> Prostate cancer
Human Diseases >> Immune disease >> Rheumatoid arthritis
Environmental Information Processing >> Signal transduction >> TNF signaling pathway
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Catalog: KE1172
Size
Price
Status
Qty.
5*96well
$1,850.00
2 weeks
0
2*96well
$740.00
2 weeks
0
96well
$370.00
2 weeks
0
Add to cart
Collected
Collect
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