Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

TGFB3

Transforming growth factor beta-3

TGFB3 ;
Transforming growth factor beta-3 ;
TGF-beta-3

disease:Defects in TGFB3 are a cause of familial arrhythmogenic right ventricular dysplasia 1 (ARVD1) [MIM:107970]; also known as arrhythmogenic right ventricular cardiomyopathy 1 (ARVC1) . ARVD is an autosomal dominant disease characterized by partial degeneration of the myocardium of the right ventricle , electrical instability , and sudden death. It is clinically defined by electrocardiographic and angiographic criteria; pathologic findings , replacement of ventricular myocardium with fatty and fibrous elements , preferentially involve the right ventricular free wall. ,function:Involved in embryogenesis and cell differentiation. ,online information:TGF beta-3 entry ,similarity:Belongs to the TGF-beta family. ,subunit:Homodimer; disulfide-linked. ,

protein import into nucleus , translocation , MAPKKK cascade , activation of MAPK activity , skeletal system development ,ossification , response to hypoxia , in utero embryonic development , regulation of protein amino acid phosphorylation ,positive regulation of protein amino acid phosphorylation , reproductive developmental process , detection of oxygen ,regulation of DNA replication , regulation of transcription , DNA-dependent , regulation of transcription from RNA polymerase II promoter , protein amino acid phosphorylation , protein targeting , protein import into nucleus ,phosphorus metabolic process , phosphate metabolic process , intracellular protein transport , nucleocytoplasmic transport , induction of apoptosis , cell surface receptor linked signal transduction , enzyme linked receptor protein signaling pathway , transmembrane receptor protein serine/threonine kinase signaling pathway , transforming growth factor beta receptor signaling pathway , SMAD protein nuclear translocation , intracellular signaling cascade , protein kinase cascade , sensory organ development , salivary gland development , salivary gland morphogenesis , female pregnancy , aging , protein localization , negative regulation of DNA replication , negative regulation of cell proliferation ,regulation of cell size , detection of chemical stimulus , response to wounding , response to endogenous stimulus ,response to hormone stimulus , embryonic development ending in birth or egg hatching , negative regulation of biosynthetic process , positive regulation of biosynthetic process , positive regulation of signal transduction , negative regulation of signal transduction , response to organic substance , positive regulation of macromolecule biosynthetic process , negative regulation of macromolecule biosynthetic process , positive regulation of phosphorus metabolic process , positive regulation of macromolecule metabolic process , negative regulation of macromolecule metabolic process , positive regulation of gene expression , positive regulation of cell communication , negative regulation of cell communication , regulation of collagen metabolic process , positive regulation of collagen metabolic process , regulation of epithelial to mesenchymal transition , positive regulation of epithelial to mesenchymal transition , positive regulation of cell development , regulation of cell morphogenesis involved in differentiation , positive regulation of cell morphogenesis involved in differentiation , positive regulation of pathway-restricted SMAD protein phosphorylation ,regulation of cell death , positive regulation of cell death , induction of programmed cell death , protein transport , cell growth , phosphorylation , regulation of transforming growth factor beta receptor signaling pathway , protein import ,regulation of phosphate metabolic process , menstrual cycle phase , ovulation cycle process , regulation of cell morphogenesis , gland morphogenesis , regulation of ossification , respiratory tube development , lung development ,regulation of bone mineralization , positive regulation of bone mineralization , negative regulation of transforming growth factor beta receptor signaling pathway , mammary gland development , negative regulation of cellular biosynthetic process , positive regulation of cellular biosynthetic process , regulation of cell projection organization ,positive regulation of cell projection organization , regulation of protein modification process , positive regulation of protein modification process , regulation of cellular protein metabolic process , positive regulation of cellular protein metabolic process , regulation of intracellular transport , positive regulation of intracellular transport , multicellular organism reproduction , regulation of cellular component size , response to progesterone stimulus , regulation of gene-specific transcription , regulation of protein localization , regulation of collagen biosynthetic process , positive regulation of collagen biosynthetic process , regulation of intracellular protein transport , regulation of protein import into nucleus , translocation , positive regulation of protein import into nucleus , translocation , protein localization in organelle , positive regulation of kinase activity , cell junction organization , response to fluid shear stress , protein localization in nucleus ,cellular protein localization , response to laminar fluid shear stress , exocrine system development , tube development ,growth , wound healing , regulation of cell proliferation , regulation of protein import into nucleus , regulation of phosphorylation , positive regulation of phosphorylation , odontogenesis , ovulation cycle , regulation of apoptosis ,chordate embryonic development , positive regulation of apoptosis , negative regulation of apoptosis , regulation of programmed cell death , positive regulation of programmed cell death , negative regulation of programmed cell death ,positive regulation of catalytic activity , positive regulation of gene-specific transcription , regulation of MAP kinase activity , positive regulation of MAP kinase activity , regulation of neuron apoptosis , negative regulation of neuron apoptosis , regulation of kinase activity , ear development , response to estrogen stimulus , ossification involved in bone remodeling , regulation of cellular component biogenesis , positive regulation of molecular function , regulation of multicellular organismal metabolic process , positive regulation of multicellular organismal metabolic process ,establishment of protein localization , cell-cell junction organization , regulation of transcription , positive regulation of cell differentiation , positive regulation of DNA replication , positive regulation of ossification , regulation of protein kinase activity , positive regulation of protein kinase activity , positive regulation of transcription , DNA-dependent ,negative regulation of nucleobase , nucleoside , nucleotide and nucleic acid metabolic process , positive regulation of nucleobase , nucleoside , nucleotide and nucleic acid metabolic process , positive regulation of phosphate metabolic process , positive regulation of transcription , positive regulation of transcription from RNA polymerase II promoter ,regulation of nucleocytoplasmic transport , bone remodeling , intracellular transport , lung alveolus development ,rhythmic process , response to steroid hormone stimulus , embryonic organ morphogenesis , gut development ,embryonic organ development , embryonic morphogenesis , reproductive process in a multicellular organism , embryonic cranial skeleton morphogenesis , embryonic neurocranium morphogenesis , embryonic skeletal system morphogenesis ,skeletal system morphogenesis , embryonic skeletal system development , gland development , tissue remodeling , inner ear development , regulation of protein secretion , positive regulation of protein secretion , regulation of secretion ,positive regulation of secretion , positive regulation of transport , regulation of DNA metabolic process , negative regulation of DNA metabolic process , positive regulation of DNA metabolic process , positive regulation of developmental process , positive regulation of cellular component organization , nuclear transport , nuclear import ,negative regulation of nitrogen compound metabolic process , positive regulation of nitrogen compound metabolic process , regulation of phosphorus metabolic process , positive regulation of protein transport , regulation of protein transport , positive regulation of multicellular organismal process , positive regulation of protein metabolic process ,regulation of RNA metabolic process , positive regulation of RNA metabolic process , regulation of cell division , regulation of transferase activity , positive regulation of transferase activity , regulation of filopodium assembly , positive regulation of filopodium assembly , detection of stimulus , positive regulation of cell division , palate development , regulation of cell development , regulation of cellular localization , bone development , bone morphogenesis , cranial suture morphogenesis , frontal suture morphogenesis , regulation of SMAD protein nuclear translocation , positive regulation of SMAD protein nuclear translocation , regulation of pathway-restricted SMAD protein phosphorylation , regulation of cell projection assembly , respiratory system development , negative regulation of cell death , regulation of biomineral formation , positive regulation of biomineral formation , regulation of establishment of protein localization , response to oxygen levels , detection of hypoxia , cellular macromolecule localization ,

[Latency-associated peptide]: Secreted , extracellular space , extracellular matrix .; [Transforming growth factor beta-3]: Secreted .