Catalog: KA3792C
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96well
$330.00
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Main Information
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Unmodified
Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
STEAP4
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Other Name:
Metalloreductase STEAP4 ;
Six-transmembrane epithelial antigen of prostate 4 ;
SixTransMembrane protein of prostate 2 ;
Tumor necrosis factor, alpha-induced protein 9 ;
Six-transmembrane epithelial antigen of prostate 4 ;
SixTransMembrane protein of prostate 2 ;
Tumor necrosis factor, alpha-induced protein 9 ;
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Background:
cofactor:FAD.,function:Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor.,induction:Up-regulated by androgens, including testosterone and dihydrotestosterone.,similarity:Belongs to the STEAP family.,similarity:Contains 1 ferric oxidoreductase domain.,tissue specificity:Ubiquitous. Highly expressed in placenta, lung, heart and prostate. Detected at lower levels in liver, skeletal muscle, pancreas, testis and small intestine.,
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Function:
transition metal ion transport, ion transport, cation transport, iron ion transport, di-, tri-valent inorganic cation transport, metal ion transport, fat cell differentiation, oxidation reduction,
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Cellular Localization:
Cell membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein . Early endosome membrane ; Multi-pass membrane protein .
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Tissue Expression:
Ubiquitous. Highly expressed in adipose tissue. Expressed in placenta, lung, heart and prostate. Detected at lower levels in liver, skeletal muscle, pancreas, testis and small intestine. Highly expressed in joints of patients with rheumatoid arthritis and localized with CD68 cells, a marker for macrophages.
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Reference Citation({{totalcount}})
Catalog: KA3792C
Size
Price
Status
Qty.
96well
$330.00
In stock
0
Add to cart
Collected
Collect
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