Contact Us

408-747-0189
1-877-594-3616

Quick order

Total Dok-7 Cell-Based Colorimetric ELISA Kit

-KA3775C

Main Information
Reactivity

Human, Mouse

Applications

ELISA

Conjugate/Modification


Unmodified

Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
Related Products
Primary Antibodies
Dok-7 Rabbit pAb
YT1401

More→

ELISA Kits
Total Dok-7 Cell-Based Colorimetric ELISA Kit
KA3775C

More→

ELISA Kits
Human TNF-α(Tumor Necrosis Factor Alpha) ELISA Kit
KE1372

More→

ELISA Kits
Human RNASE3/ECP(Ribonuclease A3/Eosinophil Cationic Protein) ELISA Kit
KE1709

More→

Antigen&Target Information
Gene Name:
DOK7
show all
Other Name:
Protein Dok-7 ;
Downstream of tyrosine kinase 7 ;
show all
Database Link:
Organism Gene ID SwissProt
Human 285489; Q18PE1;
Mouse Q18PE0;
Background:
disease:Defects in DOK7 are the cause of familial limb-girdle myasthenia autosomal recessive (LGM) [MIM:254300]; also called congenital myasthenic syndrome type 1B or CMS1B. LGM is a congenital myasthenic syndrome characterized by a typical 'limb girdle' pattern of muscle weakness with small, simplified neuromuscular junctions but normal acetylcholine receptor and acetylcholinesterase function.,function:Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK.,similarity:Contains 1 IRS-type PTB domain.,similarity:Contains 1 PH domain.,subcellular location:Accumulates at neuromuscular junctions.,subunit:Interacts with the cytoplasmic part of MUSK.,tissue specificity:Preferentiall eypressed in skeletal muscle and heart Present in thigh muscle, diaphragm and heart but not in the liver or spleen (at protein level).,
show all
Cellular Localization:
Cell membrane ; Peripheral membrane protein . Cell junction, synapse . Accumulates at neuromuscular junctions. .
show all
Tissue Expression:
Preferentially expressed in skeletal muscle and heart. Present in thigh muscle, diaphragm and heart but not in the liver or spleen (at protein level).
show all
Catalog: KA3775C
Size
Price
Status
Qty.
96well
$330.00
In stock

0

Add to cart

Collect

Customized Service

Recently Viewed Products

Clear all

    Toggle night Mode

    Catalog:
    Filter:

    All

    -

    Filter:

    Main Information
    Conjugate/Modification
    /
    Learn more
    Product /0
    Prev
    Next

    Scroll wheel zooms the picture