Human TNF-α(Tumor Necrosis Factor Alpha) ELISA Kit
KE1372
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ELISA Kits
Human RNASE3/ECP(Ribonuclease A3/Eosinophil Cationic Protein) ELISA Kit
KE1709
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Antigen&Target Information
Gene Name:
NR1I3
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Other Name:
Nuclear receptor subfamily 1 group I member 3 ;
Constitutive activator of retinoid response ;
Constitutive active response ;
Constitutive androstane receptor ;
CAR ;
Orphan nuclear receptor MB67 ;
domain:Composed by a short N-terminal domain followed by the DNA binding, hinge, and ligand binding/dimerization domains.,function:Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element.,induction:By dexamethasone.,similarity:Belongs to the nuclear hormone receptor family.,similarity:Belongs to the nuclear hormone receptor family. NR1 subfamily.,similarity:Contains 1 nuclear receptor DNA-binding domain.,subunit:Heterodimer of NR1I3 and RXR. Interacts with PSMC4.,tissue specificity:Predominantly expressed in liver.,
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Function:
transcription, regulation of transcription, DNA-dependent, regulation of transcription, regulation of RNA metabolic process,
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Cellular Localization:
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Recruited to the cytoplasm by DNAJC7. .