Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

TNFSF15

Tumor necrosis factor ligand superfamily member 15

TNFSF15 ;
TL1 ;
VEGI ;
Tumor necrosis factor ligand superfamily member 15 ;
TNF ligand-related molecule 1 ;
Vascular endothelial cell growth inhibitor

function:Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro) . Promotes activation of caspases and apoptosis. ,induction:Up-regulated by IL-1-alpha and TNF-alpha. ,similarity:Belongs to the tumor necrosis factor family. ,subunit:Homotrimer. ,tissue specificity:Specifically expressed in endothelial cells. Detected in monocytes , placenta , lung , liver , kidney , skeletal muscle , pancreas , spleen , prostate , small intestine and colon. ,

regulation of cytokine production , regulation of endothelial cell proliferation , negative regulation of endothelial cell proliferation , apoptosis , activation of caspase activity , immune response , intracellular signaling cascade , protein kinase cascade , I-kappaB kinase/NF-kappaB cascade , activation of NF-kappaB-inducing kinase activity , cell death ,negative regulation of cell proliferation , regulation of cell death , positive regulation of peptidase activity , programmed cell death , death , regulation of phosphate metabolic process , activation of protein kinase activity , regulation of protein localization , positive regulation of kinase activity , cytokine metabolic process , regulation of cell proliferation , regulation of phosphorylation , regulation of apoptosis , regulation of programmed cell death , positive regulation of catalytic activity , positive regulation of caspase activity , regulation of caspase activity , regulation of kinase activity , positive regulation of molecular function , regulation of protein kinase activity , positive regulation of protein kinase activity ,regulation of cytokine secretion , regulation of protein secretion , positive regulation of protein secretion , positive regulation of cytokine secretion , regulation of secretion , positive regulation of secretion , positive regulation of transport , regulation of phosphorus metabolic process , positive regulation of protein transport , regulation of protein transport , regulation of hydrolase activity , regulation of transferase activity , positive regulation of hydrolase activity ,positive regulation of transferase activity , regulation of peptidase activity , regulation of endopeptidase activity ,regulation of cellular localization , regulation of establishment of protein localization ,

Membrane ; Single-pass type II membrane protein .; [Tumor necrosis factor ligand superfamily member 15 , secreted form]: Secreted.