Catalog: KE1046
Size
Price
Status
Qty.
5*96well
$1,850.00
2 weeks
0
2*96well
$740.00
2 weeks
0
96well
$370.00
2 weeks
0
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Collected
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Main Information
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Unmodified
Detailed Information
Specificity
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Storage
2-8°C/6 months,Ship by ice bag
Modification
Unmodified
Sample Type
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Detection Method
Colorimetric
Sensitivity
15.625-2000pg/mL
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Antigen&Target Information
Specificity:
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
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Gene Name:
CXCL11 ITAC SCYB11 SCYB9B
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Protein Name:
C-X-C motif chemokine 11
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Other Name:
CXCL11 ;
ITAC ;
SCYB11 ;
SCYB9B ;
C-X-C motif chemokine 11 ;
Beta-R1 ;
H174 ;
Interferon gamma-inducible protein 9 ;
IP-9 ;
Interferon-inducible T-cell alpha chemoattractant ;
I-TAC ;
Small-inducible cytokine B11
ITAC ;
SCYB11 ;
SCYB9B ;
C-X-C motif chemokine 11 ;
Beta-R1 ;
H174 ;
Interferon gamma-inducible protein 9 ;
IP-9 ;
Interferon-inducible T-cell alpha chemoattractant ;
I-TAC ;
Small-inducible cytokine B11
show all
Background:
disease:Expressed in a variety of skin disorders , including allergic contact dermatitis , lichen planus and mycosis fungoides. ,function:Chemotactic for interleukin-activated T-cells but not unstimulated T-cells , neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses. ,induction:By interferon gamma and interferon beta. Induction by IFN-gamma is enhanced by TNF-alpha in monocytes , dermal fibroblasts and endothelial cells , and by IL-1 in astrocytes. ,mass spectrometry: PubMed:10233762 ,online information:CXCL11 entry ,similarity:Belongs to the intercrine alpha (chemokine CxC) family. ,tissue specificity:High levels in peripheral blood leukocytes , pancreas and liver astrocytes. Moderate levels in thymus , spleen and lung. Low levels in placenta , prostate and small intestine. Also found in epidermal basal layer keratinocytes in skin disorders. ,
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Function:
chemotaxis , defense response , inflammatory response , immune response , cell surface receptor linked signal transduction , G-protein coupled receptor protein signaling pathway , cell-cell signaling , behavior , locomotory behavior ,response to wounding , taxis ,
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Cellular Localization:
Secreted.
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Signaling Pathway
Organismal Systems >> Immune system >> Toll-like receptor signaling pathway
Organismal Systems >> Immune system >> Chemokine signaling pathway
Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction
Environmental Information Processing >> Signaling molecules and interaction >> Viral protein interaction with cytokine and cytokine receptor
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Catalog: KE1046
Size
Price
Status
Qty.
5*96well
$1,850.00
2 weeks
0
2*96well
$740.00
2 weeks
0
96well
$370.00
2 weeks
0
Add to cart
Collected
Collect
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