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Total N33 Cell-Based Colorimetric ELISA Kit

-KA3713C

Main Information
Reactivity

Human, Mouse, Rat

Applications

ELISA

Conjugate/Modification


Unmodified

Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
TUSC3
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Other Name:
Tumor suppressor candidate 3 ;
Magnesium uptake/transporter TUSC3 ;
Protein N33 ;
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Database Link:
Organism Gene ID SwissProt
Human 7991; Q13454;
Mouse Q8BTV1;
Background:
disease:Defects in TUSC3 are the cause of mental retardation non-syndromic autosomal recessive type 7 (MRT7) [MIM:611093]. Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.,function:May be involved in N-glycosylation through its association with N-oligosaccharyl transferase.,similarity:Belongs to the OST3/OST6 family.,subunit:Weakly associates with the oligosaccharyl transferase (OST) complex which contains at least RPN1/ribophorin I, RPN2/ribophorin II, OST48, DAD1, and either STT3A or STT3B.,tissue specificity:Expressed in most non-lymphoid cells and tissues examined, including prostate, lung, liver, colon, heart, kidney and pancreas.,
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Function:
protein amino acid glycosylation, protein amino acid N-linked glycosylation, glycoprotein metabolic process,glycoprotein biosynthetic process, peptidyl-asparagine modification, protein amino acid N-linked glycosylation via asparagine, biopolymer glycosylation, glycosylation,
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Cellular Localization:
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
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Tissue Expression:
Expressed in most non-lymphoid cells and tissues examined, including prostate, lung, liver, colon, heart, kidney and pancreas.
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Catalog: KA3713C
Size
Price
Status
Qty.
96well
$330.00
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