TBX2

T-box transcription factor TBX2 ;
T-box protein 2 ;

function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation.,similarity:Contains 1 T-box DNA-binding domain.,tissue specificity:Expressed primarily in adult in kidney, lung, and placenta. Weak expression in heart and ovary.,

negative regulation of transcription from RNA polymerase II promoter, cell fate determination, heart morphogenesis,transcription, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter,heart development, muscle organ development, muscle cell fate determination, aging, cell aging, positive regulation of cell proliferation, negative regulation of biosynthetic process, negative regulation of macromolecule biosynthetic process, negative regulation of macromolecule metabolic process, negative regulation of gene expression, striated muscle tissue development, negative regulation of transcription, mammary gland development, negative regulation of cellular biosynthetic process, regulation of cell proliferation, muscle cell differentiation, muscle cell fate commitment, cell fate commitment, regulation of transcription, negative regulation of transcription, DNA-dependent, negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, gland development, cardiac muscle tissue development, negative regulation of nitrogen compound metabolic process, regulation of RNA metabolic process,negative regulation of RNA metabolic process, muscle tissue development,

Nucleus .

Expressed primarily in adult in kidney, lung, and placenta. Weak expression in heart and ovary.