KLF10/11

function:Transcriptional repressor involved in the regulation of cell growth. Inhibits cell growth. Binds to the consensus sequence 5'-GGTGTG-3'.,induction:By TGF-beta.,PTM:Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.,similarity:Belongs to the Sp1 C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,

negative regulation of transcription from RNA polymerase II promoter, skeletal system development, ossification,regulation of myeloid leukocyte differentiation, positive regulation of myeloid leukocyte differentiation, transcription,regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, induction of apoptosis, cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway,transmembrane receptor protein serine/threonine kinase signaling pathway, transforming growth factor beta receptor signaling pathway, cell-cell signaling, cell proliferation, negative regulation of cell proliferation, negative regulation of biosynthetic process, response to organic substance, negative regulation of macromolecule biosynthetic process,negative regulation of macromolecule metabolic process, negative regulation of gene expression, regulation of cell death, positive regulation of cell death, induction of programmed cell death, negative regulation of transcription, bone mineralization, biomineral formation, negative regulation of cellular biosynthetic process, regulation of cell proliferation, regulation of apoptosis, positive regulation of apoptosis, regulation of programmed cell death, positive regulation of programmed cell death, regulation of transcription, positive regulation of cell differentiation, regulation of myeloid cell differentiation, positive regulation of myeloid cell differentiation, regulation of osteoclast differentiation,positive regulation of osteoclast differentiation, negative regulation of transcription, DNA-dependent, negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, positive regulation of developmental process, negative regulation of nitrogen compound metabolic process, regulation of RNA metabolic process, negative regulation of RNA metabolic process, response to protein stimulus, bone development,

Nucleus .