Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

FST

Follistatin

FST ;
Follistatin ;
FS ;
Activin-binding protein

function:Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH) . ,similarity:Contains 1 TB (TGF-beta binding) domain. ,similarity:Contains 3 follistatin-like domains. ,similarity:Contains 3 Kazal-like domains. ,subunit:Monomer . ,tissue specificity:Isoform 1 is the predominant isoform in serum but is undetectable in follicular fluid. ,

negative regulation of transcription from RNA polymerase II promoter , hair follicle development , reproductive developmental process , regulation of transcription , DNA-dependent , regulation of transcription from RNA polymerase II promoter , cell surface receptor linked signal transduction , enzyme linked receptor protein signaling pathway ,transmembrane receptor protein serine/threonine kinase signaling pathway , gamete generation , pattern specification process , ectoderm development , sex differentiation , cell proliferation , gonad development , epidermis development ,female gonad development , negative regulation of biosynthetic process , negative regulation of macromolecule biosynthetic process , negative regulation of macromolecule metabolic process , negative regulation of gene expression , negative regulation of transcription , sexual reproduction , molting cycle process , hair cycle process , BMP signaling pathway , hair follicle morphogenesis , negative regulation of cellular biosynthetic process , regulation of gonadotropin secretion , negative regulation of gonadotropin secretion , multicellular organism reproduction , molting cycle , odontogenesis of dentine-containing tooth , odontogenesis , hair cycle , regulation of hair cycle , keratinocyte proliferation , regulation of system process , development of primary sexual characteristics , regulation of transcription ,negative regulation of cell differentiation , regulation of epidermis development , positive regulation of epidermis development , negative regulation of transcription , DNA-dependent , negative regulation of nucleobase , nucleoside , nucleotide and nucleic acid metabolic process , development of primary female sexual characteristics , female sex differentiation , regulation of follicle-stimulating hormone secretion , negative regulation of follicle-stimulating hormone secretion , regulation of hormone secretion , negative regulation of hormone secretion , reproductive structure development , reproductive process in a multicellular organism , tissue morphogenesis , epidermis morphogenesis ,regulation of secretion , negative regulation of secretion , negative regulation of transport , positive regulation of developmental process , negative regulation of nitrogen compound metabolic process , positive regulation of multicellular organismal process , regulation of RNA metabolic process , negative regulation of RNA metabolic process ,regulation of hair follicle development , positive regulation of hair follicle development , regulation of cellular localization ,

Secreted.