Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

CNTF

Ciliary neurotrophic factor

CNTF ;
Ciliary neurotrophic factor ;
CNTF

disease:Overexpressed in most acute myelogenous leukemia (AML) cases (27 over 29) . ,function:CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. ,function:May be involved in transcriptional regulation. May play an important role in cell proliferation and/or anti-apoptosis. ,online information:Ciliary neurotrophic factor entry ,similarity:Belongs to the CNTF family. ,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family. ,similarity:Contains 5 C2H2-type zinc fingers. ,subunit:Homodimer. ,tissue specificity:Expressed ubiquitously , particularly at high level in testis. Isoform 2 is testis specific. ,tissue specificity:Nervous system. ,

regulation of cell growth , cell activation , regulation of protein amino acid phosphorylation , positive regulation of protein amino acid phosphorylation , transcription , protein complex assembly , cellular ion homeostasis , muscle organ development , positive regulation of cell proliferation , regulation of cell size , positive regulation of signal transduction ,glial cell differentiation , positive regulation of phosphorus metabolic process , positive regulation of macromolecule metabolic process , regulation of protein kinase cascade , positive regulation of cell communication , positive regulation of cell development , positive regulation of protein kinase cascade , regulation of cell morphogenesis involved in differentiation , regulation of cell death , regulation of neuron projection development , positive regulation of neuron projection development , astrocyte development , regulation of phosphoinositide 3-kinase cascade , positive regulation of phosphoinositide 3-kinase cascade , regulation of phosphate metabolic process , cytokine-mediated signaling pathway , cellular homeostasis , glial cell development , regulation of cell morphogenesis , neuron differentiation ,positive regulation of cell growth , regulation of cell projection organization , positive regulation of cell projection organization , regulation of protein modification process , positive regulation of protein modification process , regulation of response to external stimulus , positive regulation of response to external stimulus , regulation of cellular protein metabolic process , positive regulation of cellular protein metabolic process , regulation of cellular component size ,growth , regulation of growth , gliogenesis , regulation of cell proliferation , regulation of phosphorylation , positive regulation of phosphorylation , regulation of membrane potential , regulation of tyrosine phosphorylation of STAT protein , regulation of tyrosine phosphorylation of Stat3 protein , positive regulation of tyrosine phosphorylation of Stat3 protein , positive regulation of tyrosine phosphorylation of STAT protein , homeostatic process , regulation of apoptosis , negative regulation of apoptosis , regulation of programmed cell death , negative regulation of programmed cell death , regulation of MAPKKK cascade , positive regulation of MAPKKK cascade , regulation of neuron apoptosis ,negative regulation of neuron apoptosis , neuroprotection , macromolecular complex subunit organization , regulation of transcription , negative regulation of cell differentiation , positive regulation of cell differentiation , regulation of neuron differentiation , negative regulation of neuron differentiation , positive regulation of cell size , positive regulation of growth , positive regulation of phosphate metabolic process , regulation of JAK-STAT cascade , positive regulation of JAK-STAT cascade , regulation of photoreceptor cell differentiation , negative regulation of photoreceptor cell differentiation , regulation of retinal cell programmed cell death , regulation of hormone secretion , positive regulation of hormone secretion , astrocyte activation , positive regulation of response to stimulus , muscle organ morphogenesis ,neuron development , regulation of axon regeneration , positive regulation of axon regeneration , astrocyte differentiation , chemical homeostasis , regulation of peptidyl-tyrosine phosphorylation , positive regulation of peptidyl-tyrosine phosphorylation , regulation of neurogenesis , positive regulation of neurogenesis , regulation of axonogenesis , positive regulation of axonogenesis , ion homeostasis , regulation of secretion , positive regulation of secretion , positive regulation of transport , positive regulation of developmental process , positive regulation of cellular component organization , regulation of phosphorus metabolic process , negative regulation of multicellular organismal process , positive regulation of protein metabolic process , protein oligomerization , protein heterooligomerization ,regulation of nervous system development , cellular chemical homeostasis , regulation of resting membrane potential ,membrane hyperpolarization , regulation of cell development , regulation of cellular localization , negative regulation of cell death , macromolecular complex assembly , ciliary neurotrophic factor-mediated signaling pathway , protein complex biogenesis , regulation of neuron projection regeneration , positive regulation of neuron projection regeneration ,regulation of cellular response to stress ,

Cytoplasm.