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Total TMPRSS3 Cell-Based Colorimetric ELISA Kit

-KA3653C

Catalog: KA3653C
Size
Price
Status
Qty.
96well
$330.00
In stock

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Main Information
Reactivity

Human, Mouse

Applications

ELISA

Conjugate/Modification


Unmodified

Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
TMPRSS3
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Other Name:
Transmembrane protease serine 3 ;
Serine protease TADG-12 ;
Tumor-associated differentially-expressed gene 12 protein ;
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Database Link:
Organism Gene ID SwissProt
Human 64699; P57727;
Mouse Q8K1T0;
Background:
disease:Defects in TMPRSS3 are a cause of non-syndromic sensorineural deafness autosomal recessive type 10 (DFNB10) [MIM:605316].,disease:Defects in TMPRSS3 are the cause of non-syndromic sensorineural deafness autosomal recessive type 8 (DFNB8) [MIM:601072]. DFNA8 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.,function:Probable protease. Seems to be capable of activating ENaC.,PTM:Undergoes autoproteolytic activation.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 LDL-receptor class A domain.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 1 SRCR domain.,tissue specificity:Expressed in many tissues including fetal cochlea. Isoform T is found at increased levels in some carcinomas.,
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Function:
proteolysis, cellular ion homeostasis, cellular metal ion homeostasis, cellular sodium ion homeostasis, cellular homeostasis, cellular cation homeostasis, cellular monovalent inorganic cation homeostasis, homeostatic process,chemical homeostasis, ion homeostasis, metal ion homeostasis, monovalent inorganic cation homeostasis, sodium ion homeostasis, cation homeostasis, cellular chemical homeostasis,
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Cellular Localization:
Endoplasmic reticulum membrane ; Single-pass type II membrane protein .
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Tissue Expression:
Expressed in many tissues including fetal cochlea. Isoform T is found at increased levels in some carcinomas.
show all
Catalog: KA3653C
Size
Price
Status
Qty.
96well
$330.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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