ADRA2C

Alpha-2C adrenergic receptor ;
Alpha-2 adrenergic receptor subtype C4 ;
Alpha-2C adrenoreceptor ;
Alpha-2C adrenoceptor ;
Alpha-2CAR ;

function:Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.,polymorphism:The Del322-325 variant has a significant loss of function. It is approximately 10 times more frequent in African-Americans compared with Caucasians (allele frequencies 0.381 versus 0.040).,similarity:Belongs to the G-protein coupled receptor 1 family.,

MAPKKK cascade, activation of MAPK activity, protein amino acid phosphorylation, phosphorus metabolic process,phosphate metabolic process, cell surface receptor linked signal transduction, G-protein coupled receptor protein signaling pathway, intracellular signaling cascade, protein kinase cascade, cell-cell signaling, phosphorylation,regulation of phosphate metabolic process, positive regulation of kinase activity, regulation of phosphorylation,positive regulation of catalytic activity, regulation of MAP kinase activity, positive regulation of MAP kinase activity,regulation of kinase activity, positive regulation of molecular function, regulation of protein kinase activity, positive regulation of protein kinase activity, regulation of phosphorus metabolic process, regulation of transferase activity,positive regulation of transferase activity,

Cell membrane; Multi-pass membrane protein.