domain:RII-binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer.,function:May function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction.,PTM:Phosphorylated on tyrosine residues.,similarity:Belongs to the AKAP110 family.,subcellular location:Ribs of the fibrous sheath in the principal piece of the sperm tail. Dorsal margin of the acrosomal segment.,subunit:Interacts with ROPN1 AND ROPN1L.,tissue specificity:Testis specific; only expressed in spermatids.,
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Function:
exocytosis, cell motion, cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway, transmembrane receptor protein serine/threonine kinase signaling pathway, single fertilization, acrosome reaction, protein localization, fertilization, vesicle-mediated transport, calcium ion-dependent exocytosis, sexual reproduction, secretion by cell, secretion, reproductive cellular process,
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Cellular Localization:
Cytoplasmic vesicle, secretory vesicle, acrosome . Ribs of the fibrous sheath in the principal piece of the sperm tail. Dorsal margin of the acrosomal segment.