DGKI

Diacylglycerol kinase iota ;
DAG kinase iota ;
Diglyceride kinase iota ;
DGK-iota ;

catalytic activity:ATP + 1,2-diacylglycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.,similarity:Belongs to the eukaryotic diacylglycerol kinase family.,similarity:Contains 1 DAGKc domain.,similarity:Contains 2 ANK repeats.,similarity:Contains 2 phorbol-ester/DAG-type zinc fingers.,

cell surface receptor linked signal transduction, G-protein coupled receptor protein signaling pathway, activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway, intracellular signaling cascade,regulation of phosphate metabolic process, activation of protein kinase activity, positive regulation of kinase activity,regulation of phosphorylation, positive regulation of catalytic activity, regulation of kinase activity, positive regulation of molecular function, regulation of protein kinase activity, positive regulation of protein kinase activity, regulation of phosphorus metabolic process, regulation of transferase activity, positive regulation of transferase activity,

Cell projection, axon . Cell projection, dendrite . Cell junction, synapse, presynapse . Cell junction, synapse, postsynapse . Cell junction, synapse, postsynaptic density . Cell junction, synapse, synaptic cell membrane . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane . Cytoplasm, cytosol . Nucleus . Excluded from inhibitory synapses (By similarity). Localization between cytoplasm and nucleus is regulated by protein kinase C (PubMed:9830018). Both in the detergent soluble and particulate fractions (By similarity). .

Specifically expressed in brain and retina (PubMed:9830018). In brain, highly expressed in hippocampus, caudate nucleus, occipital pole, cerebral cortex, and cerebellum (PubMed:9830018). Also detected in kidney (PubMed:15894621).