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Total APRIL Cell-Based Colorimetric ELISA Kit

-KA3495C

Catalog: KA3495C
Size
Price
Status
Qty.
96well
$330.00
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Main Information
Reactivity

Human, Mouse, Rat

Applications

ELISA

Conjugate/Modification


Unmodified

Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
TNFSF13
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Other Name:
Tumor necrosis factor ligand superfamily member 13 ;
A proliferation-inducing ligand ;
APRIL ;
TNF- and APOL-related leukocyte expressed ligand 2 ;
TALL-2 ;
TNF-related death ligand 1 ;
TRDL-1 ;
CD antigen CD256 ;
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Database Link:
Organism Gene ID SwissProt
Human 8741; O75888;
Mouse Q9D777;
Background:
function:Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines.,function:Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. May be implicated in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes.,induction:Down-regulated by phorbol myristate acetate/ionomycin treatment.,PTM:The precursor is cleaved by furin.,PTM:The soluble form derives from the membrane form by proteolytic processing.,similarity:Belongs to the tumor necrosis factor family.,subunit:Homotrimer (Potential). Interacts with the angiogenic factor AGGF1/VG5Q.,subunit:Homotrimer .,tissue specificity:Expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages.,tissue specificity:Highly expressed in adult heart, pancreas, skeletal muscle, brain, colon, small intestine, lung, ovary, prostate, spleen, lymph node, appendix and peripheral blood lymphocytes. Low expression in kidney, testis, liver, placenta, thymus and bone marrow. Also detected in fetal kidney, liver, lung and brain.,
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Cellular Localization:
Secreted .
show all
Tissue Expression:
Expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages.
show all
Catalog: KA3495C
Size
Price
Status
Qty.
96well
$330.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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