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Total LMX1B Cell-Based Colorimetric ELISA Kit

-KA3477C

Catalog: KA3477C
Size
Price
Status
Qty.
96well
$330.00
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Main Information
Reactivity

Human, Mouse

Applications

ELISA

Conjugate/Modification


Unmodified

Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
LMX1B
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Other Name:
LIM homeobox transcription factor 1-beta ;
LIM/homeobox protein 1.2 ;
LMX-1.2 ;
LIM/homeobox protein LMX1B ;
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Database Link:
Organism Gene ID SwissProt
Human 4010; O60663;
Mouse O88609;
Background:
disease:Defects in LMX1B are the cause of nail-patella syndrome (NPS) [MIM:161200]; also knowan as Onychoosteodysplasia. NPS is a disease that cause abnormal skeletal patterning and renal dysplasia.,function:Essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 LIM zinc-binding domain.,similarity:Contains 2 LIM zinc-binding domains.,tissue specificity:Expressed in most tissues. Highest levels in testis, thyroid, duodenum, skeletal muscle, and pancreatic islets.,
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Function:
eye development, in utero embryonic development, neuron migration, regionalization, transcription, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, cell motion, pattern specification process, sensory organ development, cell death, cell proliferation, embryonic development ending in birth or egg hatching, positive regulation of biosynthetic process, dorsal/ventral pattern formation, positive regulation of macromolecule biosynthetic process, positive regulation of macromolecule metabolic process, positive regulation of gene expression, death, cell migration, cerebellum development, hindbrain morphogenesis, cerebellum morphogenesis, central nervous system neuron differentiation, central nervous system neuron development,metencephalon development, neuron differentiation, extracellular matrix organization, collagen fibril organization,hindbrain development, positive regulation of cellular biosynthetic process, organ growth, growth, chordate embryonic development, camera-type eye development, extracellular structure organization, regulation of transcription, positive regulation of transcription, DNA-dependent, positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, positive regulation of transcription, positive regulation of transcription from RNA polymerase II promoter, neuron development, cell motility, positive regulation of nitrogen compound metabolic process, regulation of RNA metabolic process, positive regulation of RNA metabolic process, localization of cell,
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Cellular Localization:
Nucleus .
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Tissue Expression:
Expressed in most tissues. Highest levels in testis, thyroid, duodenum, skeletal muscle, and pancreatic islets.
show all
Catalog: KA3477C
Size
Price
Status
Qty.
96well
$330.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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