Catalog: KA3434C
Size
Price
Status
Qty.
96well
$330.00
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0
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Main Information
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Unmodified
Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
XRCC3
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Other Name:
DNA repair protein XRCC3 ;
X-ray repair cross-complementing protein 3 ;
X-ray repair cross-complementing protein 3 ;
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Background:
disease:Met-241 is associated with the development of cutaneous malignant melanoma.,function:Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the recA family. RAD51 subfamily.,subunit:Interacts with RAD51C and RAD51. Part of a complex consisting of RAD51B, RAD51C, RAD51D, XRCC2 and XRCC3.,
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Function:
DNA metabolic process, DNA repair, DNA recombination, response to DNA damage stimulus, cellular response to stress,
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Cellular Localization:
Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Mitochondrion. Accumulates in discrete nuclear foci prior to DNA damage, and these foci persist throughout the time course of DNA repair.
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Reference Citation({{totalcount}})
Catalog: KA3434C
Size
Price
Status
Qty.
96well
$330.00
In stock
0
Add to cart
Collected
Collect
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