alternative products:Additional isoforms seem to exist,function:Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.,PTM:VEGF-B186 is O-glycosylated.,similarity:Belongs to the PDGF/VEGF growth factor family.,subcellular location:Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.,subunit:Homodimer; disulfide-linked. Can also form heterodimer with VEGF.,tissue specificity:Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.,
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Function:
regulation of cell growth, cell proliferation, positive regulation of cell proliferation, regulation of growth, regulation of cell proliferation, regulation of cell division, positive regulation of cell division,
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Cellular Localization:
Secreted. Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.
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Tissue Expression:
Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.