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Total SENP2 Cell-Based Colorimetric ELISA Kit

-KA3415C

Catalog: KA3415C
Size
Price
Status
Qty.
96well
$330.00
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Main Information
Reactivity

Human, Mouse, Rat

Applications

ELISA

Conjugate/Modification


Unmodified

Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
SENP2
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Other Name:
Sentrin-specific protease 2 ;
Axam2 ;
SMT3-specific isopeptidase 2 ;
Smt3ip2 ;
Sentrin/SUMO-specific protease SENP2 ;
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Database Link:
Organism Gene ID SwissProt
Human 59343; Q9HC62;
Mouse Q91ZX6;
Rat Q9EQE1;
Background:
domain:The N-terminus is necessary and sufficient for nuclear envelope targeting.,function:Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway.,PTM:Polyubiquitinated; which leads to proteasomal degradation.,similarity:Belongs to the peptidase C48 family.,subcellular location:Shuttles between cytoplasm and nucleus.,subunit:Binds to SUMO2 and SUMO3 (By similarity). Interacts with the C-terminal domain of NUP153 via its N-terminus.,
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Function:
RNA localization, proteolysis, cell surface receptor linked signal transduction, protein localization, macromolecule catabolic process, protein transport, nucleobase, nucleoside, nucleotide and nucleic acid transport, Wnt receptor signaling pathway, protein desumoylation, modification-dependent protein catabolic process, regulation of Wnt receptor signaling pathway, protein catabolic process, modification-dependent macromolecule catabolic process,cellular protein catabolic process, cellular macromolecule catabolic process, establishment of protein localization,nucleic acid transport, RNA transport, mRNA transport, establishment of RNA localization, proteolysis involved in cellular protein catabolic process, transmembrane transport, protein modification by small protein removal, protein modification by small protein conjugation or removal,
show all
Cellular Localization:
Nucleus, nuclear pore complex . Nucleus membrane ; Peripheral membrane protein ; Nucleoplasmic side . Cytoplasm . Shuttles between cytoplasm and nucleus. .
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Catalog: KA3415C
Size
Price
Status
Qty.
96well
$330.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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