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Total TIMP-1 Cell-Based Colorimetric ELISA Kit

-KA3397C

Catalog: KA3397C
Size
Price
Status
Qty.
96well
$330.00
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Main Information
Reactivity

Human, Mouse, Rat

Applications

ELISA

Conjugate/Modification


Unmodified

Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
TIMP1
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Other Name:
Metalloproteinase inhibitor 1 ;
Erythroid-potentiating activity ;
EPA ;
Fibroblast collagenase inhibitor ;
Collagenase inhibitor ;
Tissue inhibitor of metalloproteinases 1 ;
TIMP-1 ;
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Database Link:
Organism Gene ID SwissProt
Human 7076; P01033;
Mouse P12032;
Rat P30120;
Background:
function:Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16. Does not act on MMP-14.,PTM:The activity of TIMP1 is dependent on the presence of disulfide bonds.,similarity:Belongs to the protease inhibitor I35 (TIMP) family.,similarity:Contains 1 NTR domain.,
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Function:
immune system development, positive regulation of cell proliferation, regulation of catabolic process, negative regulation of catabolic process, negative regulation of macromolecule metabolic process, developmental maturation,hemopoiesis, myeloid cell differentiation, regulation of proteolysis, erythrocyte differentiation, regulation of cellular catabolic process, negative regulation of cellular catabolic process, regulation of cellular protein metabolic process,negative regulation of cellular protein metabolic process, erythrocyte homeostasis, regulation of cell proliferation,regulation of protein catabolic process, negative regulation of protein catabolic process, homeostatic process,erythrocyte maturation, negative regulation of proteolysis, cell maturation, hemopoietic or lymphoid organ development, erythrocyte development, homeostasis of number of cells, regulation of membrane protein ectodomain proteolysis, negative regulation of membrane protein ectodomain proteolysis, negative regulation of protein metabolic process,
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Cellular Localization:
Secreted .
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Tissue Expression:
Detected in rheumatoid synovial fluid (at protein level).
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Catalog: KA3397C
Size
Price
Status
Qty.
96well
$330.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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