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Total Cystatin B Cell-Based Colorimetric ELISA Kit

-KA3383C

Catalog: KA3383C
Size
Price
Status
Qty.
96well
$330.00
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Main Information
Reactivity

Human, Rat

Applications

ELISA

Conjugate/Modification


Unmodified

Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
CSTB
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Other Name:
Cystatin-B ;
CPI-B ;
Liver thiol proteinase inhibitor ;
Stefin-B ;
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Database Link:
Organism Gene ID SwissProt
Human 1476; P04080;
Mouse Q62426;
Rat P01041;
Background:
disease:Defects in CSTB are the cause of progressive myoclonic epilepsy type 1 (EPM1) [MIM:254800]. EPM1 is an autosomal recessive disorder characterized by severe, stimulus-sensitive myoclonus and tonic-clonic seizures. The onset, occurring between 6 and 13 years of age, is characterized by convulsions. Myoclonus begins 1 to 5 years later. The twitchings occur predominantly in the proximal muscles of the extremities and are bilaterally symmetrical, although asynchronous. At first small, they become late in the clinical course so violent that the victim is thrown to the floor. Mental deterioration and eventually dementia develop.,function:This is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B.,similarity:Belongs to the cystatin family.,subunit:Able to form dimers stabilized by noncovalent forces.,
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Function:
behavior, locomotory behavior, adult locomotory behavior, negative regulation of peptidase activity, regulation of cell death, adult behavior, regulation of apoptosis, regulation of programmed cell death, negative regulation of catalytic activity, negative regulation of molecular function, regulation of hydrolase activity, negative regulation of hydrolase activity, regulation of peptidase activity,
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Cellular Localization:
Cytoplasm . Nucleus .
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Catalog: KA3383C
Size
Price
Status
Qty.
96well
$330.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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