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Total Rit1 Cell-Based Colorimetric ELISA Kit

-KA3372C

Catalog: KA3372C
Size
Price
Status
Qty.
96well
$330.00
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Main Information
Reactivity

Human, Mouse

Applications

ELISA

Conjugate/Modification


Unmodified

Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
RIT1
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Other Name:
GTP-binding protein Rit1 ;
Ras-like protein expressed in many tissues ;
Ras-like without CAAX protein 1 ;
show all
Database Link:
Organism Gene ID SwissProt
Human 6016; Q92963;
Mouse P70426;
Background:
enzyme regulation:Alternate between an inactive form bound to GDP and an active form bound to GTP.,function:Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation.,miscellaneous:Shows rapid uncatalyzed guanine nucleotide dissociation rates, which are much faster than those of most Ras subfamily members.,miscellaneous:Stimulation of the NGF and EGF receptor signaling pathways results in rapid and prolonged activation.,similarity:Belongs to the small GTPase superfamily. Ras family.,subunit:Interacts with MLLT4, the C-terminal domain of RALGDS and RLF, but not with RIN1 and PIK3CA. RLF binds exclusively to the active GTP-bound form. Strongly interacts with BRAF, but only weakly with RAF1. BARF and RAF1 association is dependent upon the GTP-bound state. Interacts with RGL3.,tissue specificity:Expressed in many tissues.,
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Function:
intracellular signaling cascade, small GTPase mediated signal transduction,
show all
Cellular Localization:
Cell membrane.
show all
Tissue Expression:
Expressed in many tissues.
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Catalog: KA3372C
Size
Price
Status
Qty.
96well
$330.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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