Catalog: KA3342C
Size
Price
Status
Qty.
96well
$330.00
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0
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Main Information
Reactivity
Human, Mouse
Applications
ELISA
Conjugate/Modification
Unmodified
Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
Related Products
Primary Antibodies
Oct-2 Rabbit pAb
YT3231
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ELISA Kits
Total Oct-2 Cell-Based Colorimetric ELISA Kit
KA3342C
More→
Antigen&Target Information
Gene Name:
POU2F2
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Other Name:
POU domain, class 2, transcription factor 2 ;
Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2 ;
Octamer-binding protein 2 ;
Oct-2 ;
Octamer-binding transcription factor 2 ;
OTF-2 ;
Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2 ;
Octamer-binding protein 2 ;
Oct-2 ;
Octamer-binding transcription factor 2 ;
OTF-2 ;
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Background:
function:Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter.,similarity:Belongs to the POU transcription factor family. Class-2 subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 POU-specific domain.,subunit:Interacts with NR3C1, AR and PGR.,tissue specificity:Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line Molt-4, but not in the T-cell line BW 5147.,
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Function:
transcription, transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter, immune response, humoral immune response, RNA biosynthetic process, regulation of transcription, regulation of RNA metabolic process,
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Cellular Localization:
Cytoplasm . Nucleus.
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Tissue Expression:
Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line MOLT-4, but not in the T-cell line BW5147.
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Reference Citation({{totalcount}})
Catalog: KA3342C
Size
Price
Status
Qty.
96well
$330.00
In stock
0
Add to cart
Collected
Collect
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