Catalog: KA3333C
Size
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Qty.
96well
$330.00
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0
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Main Information
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Unmodified
Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
MMP7
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Other Name:
Matrilysin ;
Matrin ;
Matrix metalloproteinase-7 ;
MMP-7 ;
Pump-1 protease ;
Uterine metalloproteinase ;
Matrin ;
Matrix metalloproteinase-7 ;
MMP-7 ;
Pump-1 protease ;
Uterine metalloproteinase ;
show all
Background:
catalytic activity:Cleavage of 14-Ala-|-Leu-15 and 16-Tyr-|-Leu-17 in B chain of insulin. No action on collagen types I, II, IV, V. Cleaves gelatin chain alpha-2(I) > alpha-1(I).,cofactor:Binds 2 calcium ions per subunit.,cofactor:Binds 2 zinc ions per subunit.,domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.,function:Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.,similarity:Belongs to the peptidase M10A family.,
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Function:
proteolysis, collagen catabolic process, collagen metabolic process, regulation of cell proliferation, multicellular organismal metabolic process, multicellular organismal catabolic process, multicellular organismal macromolecule metabolic process,
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Cellular Localization:
Secreted, extracellular space, extracellular matrix .
show all
Signaling Pathway
Reference Citation({{totalcount}})
Catalog: KA3333C
Size
Price
Status
Qty.
96well
$330.00
In stock
0
Add to cart
Collected
Collect
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