cofactor:Binds 1 zinc ion per subunit.,enzyme regulation:Inhibited by TIMP2.,function:Protease.,PTM:N-glycosylated.,PTM:Proteolytic cleavage might yield an active form.,similarity:Belongs to the peptidase M10A family.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,subcellular location:A secreted form produced by proteolytic cleavage seems also to exist.,tissue specificity:Predominantly expressed in ovary, testis and prostate.,
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Function:
proteolysis,
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Cellular Localization:
Endoplasmic reticulum membrane ; Single-pass type II membrane protein . Membrane ; Single-pass type II membrane protein . A secreted form produced by proteolytic cleavage may also exist. .
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Tissue Expression:
Predominantly expressed in ovary, testis and prostate.