Catalog: KA3323C
Size
Price
Status
Qty.
96well
$330.00
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0
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Main Information
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Unmodified
Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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KA3323C
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Antigen&Target Information
Gene Name:
MMP10
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Other Name:
Stromelysin-2 ;
SL-2 ;
Matrix metalloproteinase-10 ;
MMP-10 ;
Transin-2 ;
SL-2 ;
Matrix metalloproteinase-10 ;
MMP-10 ;
Transin-2 ;
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Background:
catalytic activity:Similar to stromelysin 1, but action on collagen types III, IV and V is weak.,cofactor:Binds 2 zinc ions per subunit.,cofactor:Calcium.,domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.,function:Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase.,similarity:Belongs to the peptidase M10A family.,similarity:Contains 4 hemopexin-like domains.,
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Function:
proteolysis, collagen catabolic process, collagen metabolic process, multicellular organismal metabolic process,multicellular organismal catabolic process, multicellular organismal macromolecule metabolic process,
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Cellular Localization:
Secreted, extracellular space, extracellular matrix .
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Reference Citation({{totalcount}})
Catalog: KA3323C
Size
Price
Status
Qty.
96well
$330.00
In stock
0
Add to cart
Collected
Collect
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