Catalog: KA3317C
Size
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96well
$330.00
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0
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Main Information
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Unmodified
Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
MLANA
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Other Name:
Melanoma antigen recognized by T-cells 1 ;
MART-1 ;
Antigen LB39-AA ;
Antigen SK29-AA ;
Protein Melan-A ;
MART-1 ;
Antigen LB39-AA ;
Antigen SK29-AA ;
Protein Melan-A ;
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Background:
tissue specificity:Expression is restricted to melanoma and melanocyte cell lines and retina.,
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Cellular Localization:
Endoplasmic reticulum membrane; Single-pass type III membrane protein. Golgi apparatus. Golgi apparatus, trans-Golgi network membrane. Melanosome. Also found in small vesicles and tubules dispersed over the entire cytoplasm. A small fraction of the protein is inserted into the membrane in an inverted orientation. Inversion of membrane topology results in the relocalization of the protein from a predominant Golgi/post-Golgi area to the endoplasmic reticulum. Melanoma cells expressing the protein with an inverted membrane topology are more effectively recognized by specific cytolytic T-lymphocytes than those expressing the protein in its native membrane orientation.
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Tissue Expression:
Expression is restricted to melanoma and melanocyte cell lines and retina.
show all
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Catalog: KA3317C
Size
Price
Status
Qty.
96well
$330.00
In stock
0
Add to cart
Collected
Collect
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