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Total Histone deacetylase 10 Cell-Based Colorimetric ELISA Kit

-KA3288C

Catalog: KA3288C
Size
Price
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Qty.
96well
$330.00
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Main Information
Reactivity

Human, Mouse, Rat

Applications

ELISA

Conjugate/Modification


Unmodified

Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
HDAC10
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Other Name:
Histone deacetylase 10 ;
HD10 ;
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Database Link:
Organism Gene ID SwissProt
Human 83933; Q969S8;
Mouse Q6P3E7;
Rat Q569C4;
Background:
catalytic activity:Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.,function:Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.,similarity:Belongs to the histone deacetylase family. Type 2 subfamily.,subcellular location:Excluded from the nucleoli.,subunit:Interacts with HDAC2, HDAC3 and NCOR2.,tissue specificity:Ubiquitous. High expression in liver, spleen, pancreas and kidney.,
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Function:
negative regulation of transcription from RNA polymerase II promoter, chromatin organization, transcription, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, protein amino acid deacetylation, negative regulation of biosynthetic process, negative regulation of macromolecule biosynthetic process,negative regulation of macromolecule metabolic process, negative regulation of gene expression, negative regulation of transcription, chromatin modification, covalent chromatin modification, histone modification, histone deacetylation,negative regulation of cellular biosynthetic process, regulation of transcription, negative regulation of transcription, DNA-dependent, negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process,negative regulation of nitrogen compound metabolic process, regulation of RNA metabolic process, negative regulation of RNA metabolic process, chromosome organization,
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Cellular Localization:
Cytoplasm . Nucleus . Excluded from nucleoli. .
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Tissue Expression:
Widely expressed with high levels in liver and kidney.
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Catalog: KA3288C
Size
Price
Status
Qty.
96well
$330.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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