GRM7

Metabotropic glutamate receptor 7 ;
mGluR7 ;

function:Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity.,similarity:Belongs to the G-protein coupled receptor 3 family.,subunit:Interacts with PICK1.,tissue specificity:Expressed in many areas of the brain, especially in the cerebral cortex, hippocampus, and cerebellum. Expression of GRM7 isoforms in non-neuronal tissues appears to be restricted to isoform 3 and isoform 4.,

conditioned taste aversion, behavioral fear response, behavioral defense response, regulation of nucleotide metabolic process, defense response, cell surface receptor linked signal transduction, G-protein coupled receptor protein signaling pathway, negative regulation of adenylate cyclase activity, cell-cell signaling, synaptic transmission, sensory perception, sensory perception of sound, sensory perception of chemical stimulus, sensory perception of smell,behavior, learning or memory, learning, memory, short-term memory, feeding behavior, associative learning, negative regulation of biosynthetic process, regulation of glutamate secretion, negative regulation of glutamate secretion,transmission of nerve impulse, adult behavior, regulation of cyclic nucleotide metabolic process, negative regulation of cyclic nucleotide metabolic process, regulation of cyclic nucleotide biosynthetic process, negative regulation of cyclic nucleotide biosynthetic process, regulation of nucleotide biosynthetic process, negative regulation of nucleotide biosynthetic process, regulation of cAMP metabolic process, negative regulation of cAMP metabolic process, regulation of cAMP biosynthetic process, negative regulation of cAMP biosynthetic process, regulation of cyclase activity, negative regulation of cyclase activity, negative regulation of cellular biosynthetic process, multicellular organismal response to stress, fear response, negative regulation of catalytic activity, negative regulation of molecular function, regulation of adenylate cyclase activity, negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, negative regulation of nucleotide metabolic process, neurological system process, cognition, sensory perception of mechanical stimulus, regulation of secretion, negative regulation of secretion, negative regulation of transport, negative regulation of nitrogen compound metabolic process, regulation of lyase activity, negative regulation of lyase activity, regulation of cellular localization,

Cell membrane ; Multi-pass membrane protein .

Expressed in many areas of the brain, especially in the cerebral cortex, hippocampus, and cerebellum. Expression of GRM7 isoforms in non-neuronal tissues appears to be restricted to isoform 3 and isoform 4.