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Total Gastrin Cell-Based Colorimetric ELISA Kit

-KA3272C

Catalog: KA3272C
Size
Price
Status
Qty.
96well
$330.00
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Main Information
Reactivity

Human, Mouse, Rat

Applications

ELISA

Conjugate/Modification


Unmodified

Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
GAST
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Other Name:
Gastrin [Cleaved into: Gastrin-71 ;
Gastrin component I ;
Gastrin-52 ;
G52 ;
Big gastrin ;
Gastrin component II ;
Gastrin-34 ;
G34 ;
Gastrin ;
Gastrin component III ;
Gastrin-17 ;
G17 ;
Gastrin-14 ;
G14 ;
Gastrin-6 ;
G6 ;
]
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Database Link:
Organism Gene ID SwissProt
Human 2520; P01350;
Mouse P48757;
Rat P04563;
Background:
function:Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine.,online information:Gastrin entry,PTM:Sulfation enhances proteolytic processing, and blocks peptide degradation. Levels of sulfation differ between proteolytically-cleaved gastrins. Thus, gastrin-6 is almost 73% sulfated, whereas the larger gastrins are less than 50% sulfated. Sulfation levels are also tissue-specific.,PTM:Two different processing pathways probably exist in antral G-cells. In the dominant pathway progastrin is cleaved at three sites resulting in two major bioactive gastrins, gastrin-34 and gastrin-17. In the putative alternative pathway, progastrin may be processed only at the most C-terminal dibasic site resulting in the synthesis of gastrin-71.,similarity:Belongs to the gastrin/cholecystokinin family.,
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Function:
cell surface receptor linked signal transduction, G-protein coupled receptor protein signaling pathway,
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Cellular Localization:
Secreted.
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Catalog: KA3272C
Size
Price
Status
Qty.
96well
$330.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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