developmental stage:G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis.,function:Likely to be involved in the control of the cell cycle during S phase and G2.,similarity:Belongs to the cyclin family.,similarity:Belongs to the cyclin family. Cyclin AB subfamily.,similarity:Contains 1 F-box domain.,
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Function:
M phase of mitotic cell cycle, mitotic cell cycle, M phase, nuclear division, re-entry into mitotic cell cycle, placenta development, cell cycle, mitosis, cell cycle process, cell cycle phase, organelle fission, cell division,
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Cellular Localization:
Nucleus . Cytoplasm, perinuclear region . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Localization to the centrosome is rare in S phase cells and increases in G2 cells. Localizes to both the mother and daughter centrioles. Localization to centrosomes is not dependent on CP110. Localizes to the nucleus in G2 phase. .
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Tissue Expression:
Widely expressed, with expression detected in the heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.