Catalog: KA3089C
Size
Price
Status
Qty.
96well
$330.00
In stock
0
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Collected
Collect
Main Information
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Unmodified
Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
CSF1R
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Other Name:
Macrophage colony-stimulating factor 1 receptor ;
CSF-1 receptor ;
CSF-1-R ;
CSF-1R ;
M-CSF-R ;
Proto-oncogene c-Fms ;
CD antigen CD115 ;
CSF-1 receptor ;
CSF-1-R ;
CSF-1R ;
M-CSF-R ;
Proto-oncogene c-Fms ;
CD antigen CD115 ;
show all
Background:
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Protein tyrosine-kinase transmembrane receptor for CSF1 and IL34.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 5 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with INPPL1/SHIP2 and THOC5.,tissue specificity:Expressed in bone marrow and in differentiated blood mononuclear cells.,
show all
Function:
protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway, transmembrane receptor protein tyrosine kinase signaling pathway, cell proliferation, phosphorylation,
show all
Cellular Localization:
Cell membrane; Single-pass type I membrane protein.
show all
Tissue Expression:
Expressed in bone marrow and in differentiated blood mononuclear cells.
show all
Signaling Pathway
Organismal Systems >> Immune system >> Hematopoietic cell lineage
Organismal Systems >> Development and regeneration >> Osteoclast differentiation
Human Diseases >> Cancer: overview >> Pathways in cancer
Human Diseases >> Cancer: overview >> Transcriptional misregulation in cancer
Human Diseases >> Cancer: specific types >> Acute myeloid leukemia
Environmental Information Processing >> Signal transduction >> MAPK signaling pathway
Environmental Information Processing >> Signal transduction >> Ras signaling pathway
Environmental Information Processing >> Signal transduction >> Rap1 signaling pathway
Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway
Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction
Environmental Information Processing >> Signaling molecules and interaction >> Viral protein interaction with cytokine and cytokine receptor
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Catalog: KA3089C
Size
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96well
$330.00
In stock
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