Contact Us

408-747-0189
1-877-594-3616

Quick order

FRS2 (Phospho Tyr436) Cell-Based Colorimetric ELISA Kit

-KA1733C

Catalog: KA1733C
Size
Price
Status
Qty.
96well
$470.00
In stock

0

Add to cart

Collected

Collect

Customized Service
Main Information
Reactivity

Human, Mouse

Applications

ELISA

Conjugate/Modification


Phospho

Detailed Information
Storage
2-8°C/6 months
Modification
Phospho
Detection Method
Colorimetric
Related Products
Primary Antibodies
FRS2 Rabbit pAb
YT1792

More→

Primary Antibodies
FRS2 Rabbit pAb
YT1791

More→

Primary Antibodies
FRS2 (Phospho Tyr436) Rabbit pAb
YP0805

More→

ELISA Kits
Total FRS2 Cell-Based Colorimetric ELISA Kit
KA4101C

More→

ELISA Kits
FRS2 (Phospho Tyr436) Cell-Based Colorimetric ELISA Kit
KA1733C

More→

Antigen&Target Information
Gene Name:
FRS2
show all
Other Name:
Fibroblast growth factor receptor substrate 2 ;
FGFR substrate 2 ;
FGFR-signaling adaptor SNT ;
Suc1-associated neurotrophic factor target 1 ;
SNT-1 ;
show all
Database Link:
Organism Gene ID SwissProt
Human 10818; Q8WU20;
Mouse Q8C180;
Background:
function:Adapter protein that links FGR and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.,PTM:Phosphorylated on tyrosine residues upon stimulation by NGF.,PTM:Ubiquitinated when tyrosine phosphorylated and in a complex with GRB2. The unphosphorylated form is not subject to ubiquitination.,sequence caution:Translated as stop.,similarity:Contains 1 IRS-type PTB domain.,subcellular location:Cytoplasmic, membrane-bound.,subunit:Part of a complex containing FRS2, GRB2 and SOS1. Part of a complex containing GRB2 and CBL. Binds RET (By similarity). Binds FGFR1, SUC1, NTRK1, NTRK2, NTRK3 and SRC. The tyrosine-phosphorylated protein binds the SH2 domains of GRB2 and PTPN11.,tissue specificity:Highly expressed in heart, brain, spleen, lung, liver, skeletal muscle, kidney and testis.,
show all
Function:
MAPKKK cascade, activation of MAPK activity, embryonic axis specification, eye development, gastrulation with mouth forming second, cell fate specification, optic placode formation, induction of an organ, regionalization, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway, transmembrane receptor protein tyrosine kinase signaling pathway, transmembrane receptor protein tyrosine phosphatase signaling pathway, G-protein coupled receptor protein signaling pathway, intracellular signaling cascade, protein kinase cascade, cell-cell signaling,blastoderm segmentation, tripartite regional subdivision, gastrulation, pattern specification process, neuroblast proliferation, sensory organ development, cell proliferation, fibroblast growth factor receptor signaling pathway,determination of anterior/posterior axis, embryo, axis specification, embryonic pattern specification, anterior/posterior axis specification, anterior/posterior pattern formation, phosphorylation, regulation of phosphate metabolic process,forebrain development, embryonic camera-type eye development, developmental induction, positive regulation of kinase activity, segmentation, regulation of phosphorylation, camera-type eye development, positive regulation of catalytic activity, regulation of MAP kinase activity, positive regulation of MAP kinase activity, regulation of kinase activity, positive regulation of molecular function, cell fate commitment, cell-cell signaling involved in cell fate specification, regulation of protein kinase activity, positive regulation of protein kinase activity, optic placode formation involved in camera-type eye, embryonic eye morphogenesis, embryonic organ morphogenesis, embryonic organ development, eye morphogenesis, camera-type eye morphogenesis, embryonic camera-type eye morphogenesis,embryonic morphogenesis, regulation of phosphorus metabolic process, regulation of transferase activity, positive regulation of transferase activity,
show all
Cellular Localization:
Endomembrane system. Cytoplasmic, membrane-bound.
show all
Tissue Expression:
Highly expressed in heart, brain, spleen, lung, liver, skeletal muscle, kidney and testis.
show all
Catalog: KA1733C
Size
Price
Status
Qty.
96well
$470.00
In stock

0

Add to cart

Collected

Collect

Customized Service

Toggle night Mode

{{pinfoXq.title || ''}}

Catalog: {{pinfoXq.catalog || ''}}
Filter:

All

{{item.name}}

{{pinfo.title}}
-{{pinfo.catalog}}

Filter:

{{item.descr}}

Main Information
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
Learn more
Product {{index}}/{{pcount}}
Prev
Next

{{pvTitle}}

Scroll wheel zooms the picture
{{pvDescr}}