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LIMK1/2 (Phospho Thr505) Cell-Based Colorimetric ELISA Kit

-KA1602C

Catalog: KA1602C
Size
Price
Status
Qty.
96well
$470.00
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Main Information
Reactivity

Human, Mouse, Rat

Applications

ELISA

Conjugate/Modification


Phospho

Detailed Information
Storage
2-8°C/6 months
Modification
Phospho
Detection Method
Colorimetric
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ELISA Kits
LIMK1/2 (Phospho Thr505) Cell-Based Colorimetric ELISA Kit
KA1602C

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Antigen&Target Information
Gene Name:
LIMK2
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Other Name:
LIM domain kinase 2 ;
LIMK-2 ;
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Database Link:
Organism Gene ID SwissProt
Human 3985; P53671;
Mouse O54785;
Rat P53670;
Background:
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro.,PTM:Phosphorylated on serine and/or threonine residues by ROCK1.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 2 LIM zinc-binding domains.,subcellular location:Isoform LIMK2a is distributed in the cytoplasm and the nucleus.,subcellular location:Isoform LIMK2b occurs mainly in the cytoplasm and is scarcely translocated to the nucleus.,subunit:Binds ROCK1 and LKAP. Interacts with PARD3. Interacts with NISCH.,tissue specificity:Highest expression in the placenta; moderate level in liver, lung, kidney, and pancreas. LIMK2a is found to be more abundant then LIMK2b in liver, colon, stomach, and spleen, while in brain, kidney, and placenta LIMK2b is the dominant form. In adult lung, both LIMK2a and LIMK2b is nearly equally observed.,
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Function:
protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, gamete generation,spermatogenesis, phosphorylation, regulation of phosphate metabolic process, sexual reproduction, multicellular organism reproduction, regulation of phosphorylation, male gamete generation, reproductive process in a multicellular organism, regulation of phosphorus metabolic process,
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Cellular Localization:
Cytoplasm, cytoskeleton, spindle . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome .; [Isoform LIMK2a]: Cytoplasm . Nucleus .; [Isoform LIMK2b]: Cytoplasm . Cytoplasm, perinuclear region . Nucleus . Mainly present in the cytoplasm and is scarcely translocated to the nucleus. .
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Catalog: KA1602C
Size
Price
Status
Qty.
96well
$470.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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