Protein phosphatase 1 regulatory subunit 14A ;
17 kDa PKC-potentiated inhibitory protein of PP1 ;
Protein kinase C-potentiated inhibitor protein of 17 kDa ;
CPI-17 ;
function:Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.,similarity:Belongs to the PP1 inhibitor family.,tissue specificity:Isoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta.,
show all
Function:
regulation of phosphate metabolic process, regulation of phosphorylation, regulation of phosphorus metabolic process,
show all
Cellular Localization:
Cytoplasm .
show all
Tissue Expression:
Isoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta.