VAV2

Guanine nucleotide exchange factor VAV2 ;
VAV-2 ;

function:Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 phorbol-ester/DAG-type zinc finger.,similarity:Contains 1 SH2 domain.,similarity:Contains 2 SH3 domains.,tissue specificity:Widely expressed.,

apoptosis, induction of apoptosis, cell motion, intracellular signaling cascade, small GTPase mediated signal transduction, cell death, induction of apoptosis by extracellular signals, regulation of cell death, positive regulation of cell death, programmed cell death, induction of programmed cell death, death, cell migration, regulation of lipid metabolic process, regulation of phosphate metabolic process, cell projection organization, cell projection assembly,lamellipodium assembly, positive regulation of kinase activity, regulation of Rho protein signal transduction, regulation of phosphorylation, regulation of apoptosis, positive regulation of apoptosis, regulation of programmed cell death,positive regulation of programmed cell death, positive regulation of catalytic activity, regulation of kinase activity,regulation of lipid kinase activity, regulation of phosphoinositide 3-kinase activity, positive regulation of phosphoinositide 3-kinase activity, positive regulation of molecular function, positive regulation of lipid metabolic process, regulation of Ras protein signal transduction, cell motility, regulation of small GTPase mediated signal transduction, regulation of phosphorus metabolic process, regulation of transferase activity, positive regulation of transferase activity, localization of cell,

Widely expressed.