SNAI1

Zinc finger protein SNAI1 ;
Protein snail homolog 1 ;
Protein sna ;

function:Seems to be involved in embryonic mesoderm formation. Binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription.,similarity:Belongs to the snail C2H2-type zinc-finger protein family.,similarity:Contains 4 C2H2-type zinc fingers.,tissue specificity:Expressed in a variety of tissues with the highest expression in kidney.,

hair follicle development, ectoderm development, epidermis development, molting cycle process, hair cycle process,hair follicle morphogenesis, molting cycle, hair cycle, tissue morphogenesis, epidermis morphogenesis,

Nucleus . Cytoplasm . Once phosphorylated (probably on Ser-107, Ser-111, Ser-115 and Ser-119) it is exported from the nucleus to the cytoplasm where subsequent phosphorylation of the destruction motif and ubiquitination involving BTRC occurs. .

Expressed in a variety of tissues with the highest expression in kidney. Expressed in mesenchymal and epithelial cell lines.