Catalog: KA1535C
Size
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96well
$470.00
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Main Information
Reactivity
Human, Mouse
Applications
ELISA
Conjugate/Modification
Phospho
Detailed Information
Storage
2-8°C/6 months
Modification
Phospho
Detection Method
Colorimetric
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ELISA Kits
Total SNAI 1 Cell-Based Colorimetric ELISA Kit
KA4285C
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ELISA Kits
SNAI 1 (Phospho Ser246) Cell-Based Colorimetric ELISA Kit
KA1535C
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Antigen&Target Information
Gene Name:
SNAI1
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Other Name:
Zinc finger protein SNAI1 ;
Protein snail homolog 1 ;
Protein sna ;
Protein snail homolog 1 ;
Protein sna ;
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Background:
snail family transcriptional repressor 1(SNAI1) Homo sapiens The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. [provided by RefSeq, Jul 2008],
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Function:
Function:Seems to be involved in embryonic mesoderm formation. Binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription.,similarity:Belongs to the snail C2H2-type zinc-finger protein family.,similarity:Contains 4 C2H2-type zinc fingers.,tissue specificity:Expressed in a variety of tissues with the highest expression in kidney.,
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Cellular Localization:
Nucleus . Cytoplasm . Once phosphorylated (probably on Ser-107, Ser-111, Ser-115 and Ser-119) it is exported from the nucleus to the cytoplasm where subsequent phosphorylation of the destruction motif and ubiquitination involving BTRC occurs. .
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Tissue Expression:
Expressed in a variety of tissues with the highest expression in kidney. Expressed in mesenchymal and epithelial cell lines.
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Reference Citation({{totalcount}})
Catalog: KA1535C
Size
Price
Status
Qty.
96well
$470.00
In stock
0
Add to cart
Collected
Collect
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