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SNAI1 (Phospho Ser246) Cell-Based Colorimetric ELISA Kit

-KA1535C

Main Information
Reactivity

Human, Mouse

Applications

ELISA

Conjugate/Modification


Phospho

Detailed Information
Storage
2-8°C/6 months
Modification
Phospho
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
SNAI1
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Other Name:
Zinc finger protein SNAI1 ;
Protein snail homolog 1 ;
Protein sna ;
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Database Link:
Organism Gene ID SwissProt
Human 6615; O95863;
Mouse Q02085;
Background:
function:Seems to be involved in embryonic mesoderm formation. Binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription.,similarity:Belongs to the snail C2H2-type zinc-finger protein family.,similarity:Contains 4 C2H2-type zinc fingers.,tissue specificity:Expressed in a variety of tissues with the highest expression in kidney.,
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Function:
hair follicle development, ectoderm development, epidermis development, molting cycle process, hair cycle process,hair follicle morphogenesis, molting cycle, hair cycle, tissue morphogenesis, epidermis morphogenesis,
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Cellular Localization:
Nucleus . Cytoplasm . Once phosphorylated (probably on Ser-107, Ser-111, Ser-115 and Ser-119) it is exported from the nucleus to the cytoplasm where subsequent phosphorylation of the destruction motif and ubiquitination involving BTRC occurs. .
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Tissue Expression:
Expressed in a variety of tissues with the highest expression in kidney. Expressed in mesenchymal and epithelial cell lines.
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Catalog: KA1535C
Size
Price
Status
Qty.
96well
$470.00
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