Contact Us

408-747-0189
1-877-594-3616

Quick order

NEK9 (Phospho Thr210) Cell-Based Colorimetric ELISA Kit

-KA1516C

Catalog: KA1516C
Size
Price
Status
Qty.
96well
$470.00
In stock

0

Add to cart

Collected

Collect

Customized Service
Main Information
Reactivity

Human, Mouse, Rat

Applications

ELISA

Conjugate/Modification


Phospho

Detailed Information
Storage
2-8°C/6 months
Modification
Phospho
Detection Method
Colorimetric
Related Products
Primary Antibodies
Nek9 Rabbit pAb
YT3035

More→

Primary Antibodies
Nek9 (Phospho Thr210) Rabbit pAb
YP0564

More→

ELISA Kits
Total NEK9 Cell-Based Colorimetric ELISA Kit
KA4194C

More→

ELISA Kits
NEK9 (Phospho Thr210) Cell-Based Colorimetric ELISA Kit
KA1516C

More→

Antigen&Target Information
Gene Name:
NEK9
show all
Other Name:
Serine/threonine-protein kinase Nek9 ;
Nercc1 kinase ;
Never in mitosis A-related kinase 9 ;
NimA-related protein kinase 9 ;
NimA-related kinase 8 ;
Nek8 ;
show all
Database Link:
Organism Gene ID SwissProt
Human 91754; Q8TD19;
Mouse Q8K1R7;
Background:
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,developmental stage:Expression varied mildly across the cell cycle, with highest expression observed in G1 and stationary-phase cells.,domain:Dimerizes through its coiled-coil domain.,enzyme regulation:Activated during mitosis by intramolecular autophosphorylation. Activity and autophosphorylation is activated by manganese >> magnesium ions. Sensitive to increasing concentration of detergents. It is not cell-cycle regulated but activity is higher in G0-arrested cells.,function:Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression.,PTM:Autophosphorylated on serine and threonine residues. When complexed with FACT, exhibits markedly elevated phosphorylation on Thr-210. During mitosis, not phosphorylated on Thr-210. Phosphorylated by CDC2 in vitro.,similarity:Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 6 RCC1 repeats.,subunit:Homodimer. Binds to Ran GTPase. Has a greater affinity for Ran-GDP over Ran-GTP. Interacts with NEK6, NEK7 and BICD2. Interacts with SSRP1 and SUPT16H, the 2 subunits of the FACT complex.,tissue specificity:Most abundant in heart, liver, kidney and testis. Also expressed in smooth muscle cells and fibroblasts.,
show all
Function:
M phase of mitotic cell cycle, mitotic cell cycle, M phase, nuclear division, protein amino acid phosphorylation,phosphorus metabolic process, phosphate metabolic process, cell cycle, mitosis, phosphorylation, cell cycle process,cell cycle phase, organelle fission, cell division,
show all
Cellular Localization:
Cytoplasm . Nucleus .
show all
Tissue Expression:
Most abundant in heart, liver, kidney and testis. Also expressed in smooth muscle cells and fibroblasts.
show all
Catalog: KA1516C
Size
Price
Status
Qty.
96well
$470.00
In stock

0

Add to cart

Collected

Collect

Customized Service

Toggle night Mode

{{pinfoXq.title || ''}}

Catalog: {{pinfoXq.catalog || ''}}
Filter:

All

{{item.name}}

{{pinfo.title}}
-{{pinfo.catalog}}

Filter:

{{item.descr}}

Main Information
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
Learn more
Product {{index}}/{{pcount}}
Prev
Next

{{pvTitle}}

Scroll wheel zooms the picture
{{pvDescr}}