Catalog: KA1453C
Size
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Qty.
96well
$470.00
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0
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Main Information
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Phospho
Detailed Information
Specificity
Detects endogenous levels of EphA2/3/4 only when phosphorylated at Human:Y588/Y596, Mouse:Y589/Y596, Rat:Y597.
Storage
2-8°C/6 months
Modification
Phospho
Detection Method
Colorimetric
Related Products
Primary Antibodies
EphA2/3/4 Rabbit pAb
YT1576
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Primary Antibodies
EphA2/3/4 (Phospho Tyr588/596) Rabbit pAb
YP0550
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ELISA Kits
Total EPHA2/3/4 Cell-Based Colorimetric ELISA Kit
KA4085C
More→
ELISA Kits
EPHA2/3/4 (Phospho Tyr588/596) Cell-Based Colorimetric ELISA Kit
KA1453C
More→
Antigen&Target Information
Specificity:
Detects endogenous levels of EphA2/3/4 only when phosphorylated at Human:Y588/Y596, Mouse:Y589/Y596, Rat:Y597.
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Gene Name:
EPHA2/3/4
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Function:
protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway, transmembrane receptor protein tyrosine kinase signaling pathway, phosphorylation, neuron differentiation, ephrin receptor signaling pathway,
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Cellular Localization:
Cell membrane ; Single-pass type I membrane protein . Cell projection, ruffle membrane ; Single-pass type I membrane protein . Cell projection, lamellipodium membrane ; Single-pass type I membrane protein . Cell junction, focal adhesion . Present at regions of cell-cell contacts but also at the leading edge of migrating cells (PubMed:19573808, PubMed:20861311). Relocates from the plasma membrane to the cytoplasmic and perinuclear regions in cancer cells (PubMed:18794797). .
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Tissue Expression:
Expressed in brain and glioma tissue and glioma cell lines (at protein level). Expressed most highly in tissues that contain a high proportion of epithelial cells, e.g. skin, intestine, lung, and ovary.
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Signaling Pathway
Environmental Information Processing >> Signal transduction >> MAPK signaling pathway
Environmental Information Processing >> Signal transduction >> Ras signaling pathway
Environmental Information Processing >> Signal transduction >> Rap1 signaling pathway
Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway
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Catalog: KA1453C
Size
Price
Status
Qty.
96well
$470.00
In stock
0
Add to cart
Collected
Collect
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