Contact Us

408-747-0189
1-877-594-3616

Quick order

PEA-15 (Phospho Ser104) Cell-Based Colorimetric ELISA Kit

-KA1383C

Catalog: KA1383C
Size
Price
Status
Qty.
96well
$470.00
In stock

0

Add to cart

Collected

Collect

Customized Service
Main Information
Reactivity

Human, Mouse, Rat

Applications

ELISA

Conjugate/Modification


Phospho

Detailed Information
Storage
2-8°C/6 months
Modification
Phospho
Detection Method
Colorimetric
Related Products
Primary Antibodies
PEA-15 Rabbit pAb
YT3653

More→

Primary Antibodies
PEA-15 (Phospho Ser104) Rabbit pAb
YP0701

More→

Primary Antibodies
PEA-15 (Phospho Ser116) Rabbit pAb
YP0669

More→

ELISA Kits
Total PEA-15 Cell-Based Colorimetric ELISA Kit
KA4228C

More→

ELISA Kits
PEA-15 (Phospho Ser104) Cell-Based Colorimetric ELISA Kit
KA1383C

More→

ELISA Kits
PEA-15 (Phospho Ser116) Cell-Based Colorimetric ELISA Kit
KA1320C

More→

Antigen&Target Information
Gene Name:
PEA15
show all
Other Name:
Astrocytic phosphoprotein PEA-15 ;
15 kDa phosphoprotein enriched in astrocytes ;
Phosphoprotein enriched in diabetes ;
PED ;
show all
Database Link:
Organism Gene ID SwissProt
Human 8682; Q15121;
Mouse Q62048;
Rat Q5U318;
Background:
function:Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm (By similarity). Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface.,PTM:Phosphorylated by protein kinase C and calcium-calmodulin-dependent protein kinase. These phosphorylation events are modulated by neurotransmitters or hormones.,similarity:Contains 1 DED (death effector) domain.,subcellular location:Associated with microtubules.,subunit:Binds RPS6KA3, MAPK3 and MAPK1. Transient interaction with PLD1 and PLD2 (By similarity). Interacts with CASP8 and FADD.,tissue specificity:Ubiquitously expressed. Most abundant in tissues such as heart, brain, muscle and adipose tissue which utilize glucose as an energy source. Lower expression in glucose-producing tissues. Higher levels of expression are found in tissues from individuals with type 2 diabetes than in controls.,
show all
Function:
apoptosis, anti-apoptosis, cell death, carbohydrate transport, regulation of glucose transport, negative regulation of glucose transport, regulation of cell death, programmed cell death, death, regulation of apoptosis, negative regulation of apoptosis, regulation of programmed cell death, negative regulation of programmed cell death, regulation of glucose import, negative regulation of glucose import, negative regulation of transport, negative regulation of cell death,
show all
Cellular Localization:
Cytoplasm. Associated with microtubules.
show all
Tissue Expression:
Ubiquitously expressed. Most abundant in tissues such as heart, brain, muscle and adipose tissue which utilize glucose as an energy source. Lower expression in glucose-producing tissues. Higher levels of expression are found in tissues from individuals with type 2 diabetes than in controls.
show all
Catalog: KA1383C
Size
Price
Status
Qty.
96well
$470.00
In stock

0

Add to cart

Collected

Collect

Customized Service

Toggle night Mode

{{pinfoXq.title || ''}}

Catalog: {{pinfoXq.catalog || ''}}
Filter:

All

{{item.name}}

{{pinfo.title}}
-{{pinfo.catalog}}

Filter:

{{item.descr}}

Main Information
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
Learn more
Product {{index}}/{{pcount}}
Prev
Next

{{pvTitle}}

Scroll wheel zooms the picture
{{pvDescr}}