PTGES3

Prostaglandin E synthase 3 ;
Cytosolic prostaglandin E2 synthase ;
cPGES ;
Hsp90 co-chaperone ;
Progesterone receptor complex p23 ;
Telomerase-binding protein p23 ;

catalytic activity:(5Z,13E)-(15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate.,function:Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes.,pathway:Lipid metabolism; prostaglandin biosynthesis.,similarity:Belongs to the p23/wos2 family.,similarity:Contains 1 CS domain.,subunit:Binds to telomerase and to the progesterone receptor.,

telomere maintenance, prostaglandin biosynthetic process, DNA metabolic process, fatty acid metabolic process, fatty acid biosynthetic process, unsaturated fatty acid biosynthetic process, icosanoid metabolic process, prostanoid metabolic process, prostaglandin metabolic process, lipid biosynthetic process, organic acid biosynthetic process,telomere organization, unsaturated fatty acid metabolic process, homeostatic process, carboxylic acid biosynthetic process, icosanoid biosynthetic process, prostanoid biosynthetic process, chromosome organization, anatomical structure homeostasis,

Cytoplasm .