RPS6KA1

Ribosomal protein S6 kinase alpha-1 ;
S6K-alpha-1 ;
90 kDa ribosomal protein S6 kinase 1 ;
p90-RSK 1 ;
p90RSK1 ;
p90S6K ;
MAP kinase-activated protein kinase 1a ;
MAPK-activated protein kinase 1a ;
MAPKAP kinase 1a ;
MAPKAPK-1a ;
Ribosomal S6 kinase 1 ;
RSK-1 ;

catalytic activity:ATP + a protein = ADP + a phosphoprotein.,caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,cofactor:Magnesium.,enzyme regulation:Activated by multiple phosphorylations on threonine and serine residues.,function:Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.,PTM:Autophosphorylated on Ser-380, as part of the activation process.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 2 protein kinase domains.,subunit:Forms a complex with either ERK1 or ERK2 in quiescent cells. Transiently dissociates following mitogenic stimulation.,

protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, intracellular signaling cascade, protein kinase cascade, phosphorylation,

Nucleus. Cytoplasm.