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Csk (Phospho Ser364) Cell-Based Colorimetric ELISA Kit

-KA1241C

Catalog: KA1241C
Size
Price
Status
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96well
$470.00
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Main Information
Reactivity

Human, Mouse, Rat

Applications

ELISA

Conjugate/Modification


Phospho

Detailed Information
Storage
2-8°C/6 months
Modification
Phospho
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
CSK
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Other Name:
Tyrosine-protein kinase CSK ;
C-Src kinase ;
Protein-tyrosine kinase CYL ;
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Database Link:
Organism Gene ID SwissProt
Human 1445; P41240;
Mouse P41241;
Rat P32577;
Background:
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Specifically phosphorylates 'Tyr-504' on LCK, which acts as a negative regulatory site. Can also act on the LYN and FYN kinases.,PTM:Autophosphorylation of Tyr-304 occurs only at abnormally high CSK concentrations in vitro.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,subcellular location:Mainly cytoplasmic, also present in lipid rafts.,subunit:Interacts with PTPN8 (By similarity). Interacts with phosphorylated SIT1, PAG1, LIME1 and TGFB1I1.,tissue specificity:Expressed in lung and macrophages.,
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Function:
protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, intracellular signaling cascade, negative regulation of cell proliferation, phosphorylation, regulation of cell proliferation,
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Cellular Localization:
Cytoplasm . Cell membrane . Mainly cytoplasmic, also present in lipid rafts. .
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Tissue Expression:
Expressed in lung and macrophages.
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Catalog: KA1241C
Size
Price
Status
Qty.
96well
$470.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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