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PLCG2 (Phospho Tyr753) Cell-Based Colorimetric ELISA Kit

-KA1215C

Catalog: KA1215C
Size
Price
Status
Qty.
96well
$470.00
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Main Information
Reactivity

Human, Mouse, Rat

Applications

ELISA

Conjugate/Modification


Phospho

Detailed Information
Storage
2-8°C/6 months
Modification
Phospho
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
PLCG2
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Other Name:
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 ;
Phosphoinositide phospholipase C-gamma-2 ;
Phospholipase C-IV ;
PLC-IV ;
Phospholipase C-gamma-2 ;
PLC-gamma-2 ;
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Database Link:
Organism Gene ID SwissProt
Human 5336; P16885;
Mouse Q8CIH5;
Rat P24135;
Background:
catalytic activity:1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.,cofactor:Calcium.,function:The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.,PTM:Phosphorylated on tyrosine residues; upon ligand-induced activation of a variety of growth factor receptors and immune system receptors. Increases phospholipase activity.,similarity:Contains 1 C2 domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 PI-PLC X-box domain.,similarity:Contains 1 PI-PLC Y-box domain.,similarity:Contains 1 SH3 domain.,similarity:Contains 2 SH2 domains.,
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Function:
cell activation, response to molecule of bacterial origin, activation of immune response, cell activation during immune response, lymphocyte activation during immune response, B cell activation during immune response, mature B cell differentiation during immune response, follicular B cell differentiation, mature B cell differentiation, leukocyte activation during immune response, immune response-activating cell surface receptor signaling pathway, immune system development, leukocyte differentiation, positive regulation of immune system process, immune response-activating signal transduction, immune response-regulating signal transduction, immune response-regulating cell surface receptor signaling pathway, inositol metabolic process, inositol biosynthetic process, phospholipid metabolic process, cellular ion homeostasis, cellular calcium ion homeostasis, cellular metal ion homeostasis, immune response,cell surface receptor linked signal transduction, elevation of cytosolic calcium ion concentration, intracellular signaling cascade, phospholipid catabolic process, response to bacterium, response to organic substance, response to inorganic substance, response to metal ion, regulation of cell death, regulation of metal ion transport, lipid catabolic process, carbohydrate biosynthetic process, organophosphate metabolic process, cellular homeostasis, polyol metabolic process, regulation of transmembrane transporter activity, cellular cation homeostasis, cellular di-, tri-valent inorganic cation homeostasis, hemopoiesis, lymphocyte differentiation, B cell differentiation, response to magnesium ion, regulation of calcium ion transport via store-operated calcium channel activity, positive regulation of calcium ion transport via store-operated calcium channel activity, activation of store-operated calcium channel activity, regulation of transporter activity, positive regulation of transporter activity, regulation of ion transmembrane transporter activity,positive regulation of ion transmembrane transporter activity, response to lipopolysaccharide, inositol trisphosphate metabolic process, inositol phosphate biosynthetic process, inositol trisphosphate biosynthetic process, response to ATP, cellular carbohydrate biosynthetic process, regulation of transmembrane transport, regulation of ion transmembrane transport, B cell activation, homeostatic process, regulation of programmed cell death, negative regulation of programmed cell death, regulation of ion transport, positive regulation of ion transport, inositol phosphate metabolic process, positive regulation of molecular function, cellular lipid catabolic process, leukocyte activation, alcohol biosynthetic process, polyol biosynthetic process, lymphocyte activation, hemopoietic or lymphoid organ development, positive regulation of response to stimulus, chemical homeostasis, positive regulation of immune response, ion homeostasis, antigen receptor-mediated signaling pathway, T cell receptor signaling pathway, positive regulation of transport, cytosolic calcium ion homeostasis, regulation of calcium ion transport, positive regulation of calcium ion transport, metal ion homeostasis, di-, tri-valent inorganic cation homeostasis, calcium ion homeostasis,cation homeostasis, cellular chemical homeostasis, negative regulation of cell death,
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Signaling Pathway
Organismal Systems >> Immune system >> Platelet activation Organismal Systems >> Immune system >> Neutrophil extracellular trap formation Organismal Systems >> Immune system >> Natural killer cell mediated cytotoxicity Organismal Systems >> Immune system >> B cell receptor signaling pathway Organismal Systems >> Immune system >> Fc epsilon RI signaling pathway Organismal Systems >> Immune system >> Fc gamma R-mediated phagocytosis Organismal Systems >> Immune system >> Leukocyte transendothelial migration Organismal Systems >> Immune system >> Chemokine signaling pathway Organismal Systems >> Endocrine system >> Growth hormone synthesis, secretion and action Organismal Systems >> Endocrine system >> Thyroid hormone signaling pathway Organismal Systems >> Nervous system >> Neurotrophin signaling pathway Organismal Systems >> Sensory system >> Inflammatory mediator regulation of TRP channels Organismal Systems >> Development and regeneration >> Osteoclast differentiation Human Diseases >> Cancer: overview >> Pathways in cancer Human Diseases >> Cancer: overview >> MicroRNAs in cancer Human Diseases >> Cancer: specific types >> Hepatocellular carcinoma Human Diseases >> Cancer: specific types >> Glioma Human Diseases >> Cancer: specific types >> Non-small cell lung cancer Environmental Information Processing >> Signal transduction >> ErbB signaling pathway Environmental Information Processing >> Signal transduction >> Ras signaling pathway Environmental Information Processing >> Signal transduction >> VEGF signaling pathway Environmental Information Processing >> Signal transduction >> NF-kappa B signaling pathway Environmental Information Processing >> Signal transduction >> HIF-1 signaling pathway Environmental Information Processing >> Signal transduction >> Calcium signaling pathway Environmental Information Processing >> Signal transduction >> Phospholipase D signaling pathway
Catalog: KA1215C
Size
Price
Status
Qty.
96well
$470.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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