CDC25B

M-phase inducer phosphatase 2 ;
Dual specificity phosphatase Cdc25B ;

catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,enzyme regulation:Stimulated by B-type cyclins.,function:Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDC2 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.,PTM:Phosphorylated by BRSK1 in vitro. Phosphorylated by CHEK1, which inhibits the activity of this protein.,similarity:Belongs to the MPI phosphatase family.,similarity:Contains 1 rhodanese domain.,

M phase of mitotic cell cycle, mitotic cell cycle, M phase, nuclear division, oocyte maturation, reproductive developmental process, protein amino acid dephosphorylation, phosphorus metabolic process, phosphate metabolic process, cell cycle, mitosis, meiosis, female meiosis, female meiosis I, gamete generation, germ cell development,female gamete generation, positive regulation of cell proliferation, oocyte differentiation, dephosphorylation,regulation of phosphate metabolic process, sexual reproduction, developmental maturation, cell cycle process, cell cycle phase, multicellular organism reproduction, positive regulation of kinase activity, regulation of cell proliferation,regulation of phosphorylation, positive regulation of catalytic activity, regulation of kinase activity, positive regulation of molecular function, regulation of protein kinase activity, positive regulation of protein kinase activity, organelle fission, cell maturation, oogenesis, oocyte development, reproductive process in a multicellular organism, reproductive cellular process, regulation of phosphorus metabolic process, cell division, meiotic cell cycle, M phase of meiotic cell cycle, regulation of transferase activity, positive regulation of transferase activity,

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle pole .