Contact Us

408-747-0189
1-877-594-3616

Quick order

MAPKAPK2 (Phospho Thr334) Cell-Based Colorimetric ELISA Kit

-KA1173C

Catalog: KA1173C
Size
Price
Status
Qty.
96well
$470.00
In stock

0

Add to cart

Collected

Collect

Customized Service
Main Information
Reactivity

Human, Mouse, Rat

Applications

ELISA

Conjugate/Modification


Phospho

Detailed Information
Storage
2-8°C/6 months
Modification
Phospho
Detection Method
Colorimetric
Related Products
Primary Antibodies
MAPKAPK-2 Rabbit pAb
YT2640

More→

Primary Antibodies
MAPKAPK-2 (Phospho Ser272) Rabbit pAb
YP0819

More→

Primary Antibodies
MAPKAPK-2 (Phospho Thr222) Rabbit pAb
YP0692

More→

Primary Antibodies
MAPKAPK-2 (Phospho Thr334) Rabbit pAb
YP0577

More→

ELISA Kits
Total MAPKAPK2 Cell-Based Colorimetric ELISA Kit
KA4168C

More→

ELISA Kits
MAPKAPK2 (Phospho Ser272) Cell-Based Colorimetric ELISA Kit
KA1751C

More→

ELISA Kits
MAPKAPK2 (Phospho Thr222) Cell-Based Colorimetric ELISA Kit
KA1369C

More→

ELISA Kits
MAPKAPK2 (Phospho Thr334) Cell-Based Colorimetric ELISA Kit
KA1173C

More→

Antigen&Target Information
Gene Name:
MAPKAPK2
show all
Other Name:
MAP kinase-activated protein kinase 2 ;
MAPK-activated protein kinase 2 ;
MAPKAP kinase 2 ;
MAPKAP-K2 ;
MAPKAPK-2 ;
MK-2 ;
MK2 ;
show all
Database Link:
Organism Gene ID SwissProt
Human 9261; P49137;
Mouse P49138;
Background:
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Seems to be activated by two distinct pathways: the first involves the stimulation of p42/p44 MAPK by growth factors, the second, triggered by stress and heat shock, depends on the activation of MPK2 and upstream MAPKK/MAPKKK.,function:Its physiological substrate seems to be the small heat shock protein (HSP27/HSP25). In vitro can phosphorylate glycogen synthase at 'Ser-7' and tyrosine hydroxylase (on 'Ser-19' and 'Ser-40'). This kinase phosphorylates Ser in the peptide sequence, Hyd-X-R-X(2)-S, where Hyd is a large hydrophobic residue (By similarity). Mediates both ERK and p38 MAPK/MAPK14 dependent neutrophil responses. Participates in TNF alpha-stimulated exocytosis of secretory vesicles in neutrophils. Plays a role in phagocytosis-induced respiratory burst activity.,PTM:Phosphorylated and activated by MAP kinase.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with PHC2.,tissue specificity:Expressed in all tissues examined.,
show all
Function:
MAPKKK cascade, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process,intracellular signaling cascade, protein kinase cascade, small GTPase mediated signal transduction, Ras protein signal transduction, posttranscriptional regulation of gene expression, mRNA metabolic process, phosphorylation, regulation of RNA stability, regulation of mRNA stability, RNA stabilization, mRNA stabilization, regulation of RNA metabolic process,
show all
Cellular Localization:
Cytoplasm . Nucleus . Phosphorylation and subsequent activation releases the autoinhibitory helix, resulting in the export from the nucleus into the cytoplasm.
show all
Tissue Expression:
Expressed in all tissues examined.
show all
Catalog: KA1173C
Size
Price
Status
Qty.
96well
$470.00
In stock

0

Add to cart

Collected

Collect

Customized Service

Toggle night Mode

{{pinfoXq.title || ''}}

Catalog: {{pinfoXq.catalog || ''}}
Filter:

All

{{item.name}}

{{pinfo.title}}
-{{pinfo.catalog}}

Filter:

{{item.descr}}

Main Information
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
Learn more
Product {{index}}/{{pcount}}
Prev
Next

{{pvTitle}}

Scroll wheel zooms the picture
{{pvDescr}}