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IκB-ε (Phospho Ser22) Cell-Based Colorimetric ELISA Kit

-KA1171C

Catalog: KA1171C
Size
Price
Status
Qty.
96well
$470.00
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Main Information
Reactivity

Human, Mouse, Rat

Applications

ELISA

Conjugate/Modification


Phospho

Detailed Information
Storage
2-8°C/6 months
Modification
Phospho
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
NFKBIE
show all
Other Name:
NF-kappa-B inhibitor epsilon ;
NF-kappa-BIE ;
I-kappa-B-epsilon ;
IkB-E ;
IkB-epsilon ;
IkappaBepsilon ;
show all
Database Link:
Organism Gene ID SwissProt
Human 4794; O00221;
Mouse O54910;
Background:
function:Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c-Rel complexes.,PTM:Serine phosphorylated; followed by proteasome-dependent degradation.,similarity:Belongs to the NF-kappa-B inhibitor family.,similarity:Contains 6 ANK repeats.,subunit:Interacts with RELA, REL, NFKB1 nuclear factor NF-kappa-B p50 subunit and NFKB2 nuclear factor NF-kappa-B p52 subunit.,tissue specificity:Highly expressed in spleen, testis and lung, followed by kidney, pancreas, heart, placenta and brain. Also expressed in granulocytes and macrophages.,
show all
Function:
amino acid transport, protein localization, neutral amino acid transport, amine transport, organic acid transport, serine transport, regulation of intracellular transport, negative regulation of intracellular transport, maintenance of protein location in cell, regulation of protein localization, regulation of intracellular protein transport, regulation of protein import into nucleus, negative regulation of protein import into nucleus, D-amino acid transport, D-serine transport,regulation of transcription factor import into nucleus, negative regulation of transcription factor import into nucleus,cytoplasmic sequestering of transcription factor, maintenance of protein location, regulation of nucleocytoplasmic transport, negative regulation of nucleocytoplasmic transport, carboxylic acid transport, negative regulation of transport, cytoplasmic sequestering of protein, regulation of protein transport, negative regulation of protein transport, maintenance of location, maintenance of location in cell, regulation of cellular localization, regulation of establishment of protein localization,
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Cellular Localization:
Cytoplasm .
show all
Tissue Expression:
Highly expressed in spleen, testis and lung, followed by kidney, pancreas, heart, placenta and brain. Also expressed in granulocytes and macrophages.
show all
Catalog: KA1171C
Size
Price
Status
Qty.
96well
$470.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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