Detects endogenous levels of GSK3α/β only when phosphorylated at Human:Y279/216, Mouse:Y279/216, Rat:Y279/216.This antibody does not recognize phosphorylated at other sites.

GSK3A/GSK3B

catalytic activity:ATP + [tau protein] = ADP + [tau protein] phosphate.,function:Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer.,

regulation of carbohydrate metabolic process, protein amino acid phosphorylation, phosphorus metabolic process,phosphate metabolic process, cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway, transmembrane receptor protein tyrosine kinase signaling pathway, insulin receptor signaling pathway, response to endogenous stimulus, response to hormone stimulus, regulation of catabolic process, negative regulation of catabolic process, negative regulation of signal transduction, response to organic substance, negative regulation of macromolecule metabolic process, negative regulation of cell communication, regulation of cellular carbohydrate metabolic process, negative regulation of cellular carbohydrate metabolic process, regulation of glucose transport, negative regulation of glucose transport, regulation of UDP-glucose catabolic process, negative regulation of UDP-glucose catabolic process, regulation of glucose metabolic process, phosphorylation, regulation of cellular catabolic process, negative regulation of cellular catabolic process, response to insulin stimulus, cellular response to insulin stimulus, cellular response to hormone stimulus, negative regulation of catalytic activity, response to peptide hormone stimulus, regulation of carbohydrate catabolic process, regulation of cellular carbohydrate catabolic process,negative regulation of molecular function, negative regulation of carbohydrate metabolic process, negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, regulation of glucose import, negative regulation of glucose import, regulation of insulin receptor signaling pathway, negative regulation of insulin receptor signaling pathway, negative regulation of response to stimulus, negative regulation of transport, negative regulation of nitrogen compound metabolic process, regulation of transferase activity, negative regulation of transferase activity,